POU4F2 Antikörper (AA 301-400)
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- Target Alle POU4F2 Antikörper anzeigen
- POU4F2 (POU Domain, Class 4, Transcription Factor 2 (POU4F2))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POU4F2 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BRN3B/POU4F2
- Isotyp
- IgG
- Top Product
- Discover our top product POU4F2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- POU4F2 (POU Domain, Class 4, Transcription Factor 2 (POU4F2))
- Andere Bezeichnung
- BRN3B (POU4F2 Produkte)
- Synonyme
- BRN3.2 antikoerper, BRN3B antikoerper, Brn-3b antikoerper, Brn-3.2 antikoerper, Brn3b antikoerper, Pou4f-rs1 antikoerper, mBrn3-3R antikoerper, brn-3b antikoerper, brn3.2 antikoerper, POU4F2 antikoerper, Xbrn3b antikoerper, brn3b antikoerper, brn3b-A antikoerper, POU class 4 homeobox 2 antikoerper, POU domain, class 4, transcription factor 2 antikoerper, POU class 4 homeobox 2 L homeolog antikoerper, POU4F2 antikoerper, Pou4f2 antikoerper, pou4f2 antikoerper, po4f2 antikoerper, pou4f2.L antikoerper
- Hintergrund
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Synonyms: BRN3B, class 4, transcription factor 2, Brain specic homeobox/POU domain protein 3B, Brain-3B, Brain-specic homeobox/POU domain protein 3B, Brn-3B, BRN3.2, Brn3b POU domain transcription factor, PO4F2_HUMAN, POU class 4 homeobox 2, POU domain, POU domain class 4 transcription factor 2, POU domain protein, POU4F2.
Background: The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU (Pit-Oct-Unc) domain proteins, whereas Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor. Interestingly, Brn-3a has two functional transactivating domains, one at the amino-terminus and one at the carboxy-terminus. Brn-2 is thought to be involved in smooth muscle cell development and differentiation.
- Gen-ID
- 5458
- UniProt
- Q12837
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Sensory Perception of Sound
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