Adracalin Antikörper (AA 51-150)

Produktnummer ABIN1385752

Produktdetails anti-Adracalin Antikörper

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Bindungsspezifität: AA 51-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adracalin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adracalin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Adracalin

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Andere Bezeichnung: Adracalin (AAAS Produkte)

Synonyme: zgc:85873 antikoerper, aladin antikoerper, Aladin antikoerper, AAA antikoerper, AAASb antikoerper, ADRACALA antikoerper, ADRACALIN antikoerper, ALADIN antikoerper, D030041N15Rik antikoerper, GL003 antikoerper, aladin WD repeat nucleoporin antikoerper, achalasia, adrenocortical insufficiency, alacrimia antikoerper, aladin WD repeat nucleoporin L homeolog antikoerper, Aaas antikoerper, aaas antikoerper, aaas.L antikoerper, AAAS antikoerper

Hintergrund:

Synonyms: AAA, AAAS, AAASb, Achalasia adrenocortical insufficiency alacrimia Allgrove triple A, Achalasia adrenocortical insufficiency alacrimia, ADRACALA, Aladin, Allgrove triple A, DKFZp586G1624, GL003, AAAS_HUMAN.

Background: Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.