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Ezrin Antikörper (pTyr353)

EZR Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1355833
  • Target Alle Ezrin (EZR) Antikörper anzeigen
    Ezrin (EZR)
    Bindungsspezifität
    • 30
    • 16
    • 12
    • 11
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr353
    Reaktivität
    • 158
    • 82
    • 75
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 142
    • 15
    • 3
    • 2
    Kaninchen
    Klonalität
    • 138
    • 23
    Polyklonal
    Konjugat
    • 93
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Ezrin Antikörper ist unkonjugiert
    Applikation
    • 121
    • 54
    • 28
    • 17
    • 16
    • 15
    • 13
    • 13
    • 12
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 353.
    Immunogen
    Peptide sequence around phosphorylation site of pTyr353 (Q-D-Y (p) -E-E) derived from Human EZRIN. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Top Product
    Discover our top product EZR Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100  
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Oda, Aishima, Morimatsu, Hayashi, Shindo, Fujino, Mizuuchi, Hattori, Tanaka, Oda: "Differential ezrin and phosphorylated ezrin expression profiles between pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and invasive ductal carcinoma of the pancreas." in: Human pathology, Vol. 44, Issue 8, pp. 1487-98, (2013) (PubMed).

    Morimatsu, Aishima, Kayashima, Hayashi, Nakata, Oda, Taguchi, Tsuneyoshi, Tanaka, Oda: "Liver-intestine cadherin expression is associated with intestinal differentiation and carcinogenesis in intraductal papillary mucinous neoplasm." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 79, Issue 2, pp. 107-14, (2012) (PubMed).

    Cui, Li, Zhang, Han: "Expression of Ezrin and phosphorylated Ezrin (pEzrin) in pancreatic ductal adenocarcinoma." in: Cancer investigation, Vol. 28, Issue 3, pp. 242-7, (2010) (PubMed).

  • Target
    Ezrin (EZR)
    Andere Bezeichnung
    Ezrin (EZR Produkte)
    Synonyme
    CVIL antikoerper, CVL antikoerper, VIL2 antikoerper, ezr antikoerper, vil2 antikoerper, wu:fc05c03 antikoerper, wu:fj31d06 antikoerper, cvil antikoerper, cvl antikoerper, Vil2 antikoerper, AW146364 antikoerper, R75297 antikoerper, p81 antikoerper, ezr.S antikoerper, ezrin antikoerper, ezrin b antikoerper, ezrin L homeolog antikoerper, EZR antikoerper, ezrb antikoerper, ezr antikoerper, Ezr antikoerper, ezr.L antikoerper
    Hintergrund
    Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
    Molekulargewicht
    81 kDa
    NCBI Accession
    NP_001104
    UniProt
    P15311
    Pathways
    Maintenance of Protein Location
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