FCER2 Antikörper (PE)

Produktnummer ABIN135167

Produktdetails anti-FCER2 Antikörper (PE)

Target: FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser FCER2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse CD23, Mr 45-49 kDa

Produktmerkmale: Rat Anti-Mouse CD23-PE

Immunogen: FcR isolated from B cell lymphoma cell line M12.4.5

Klon: 2G8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ELISA - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE, APC, and PE/CY7 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

cell sorting

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu FCER2

Target: FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))

Andere Bezeichnung: CD23 (FCER2 Produkte)

Synonyme: BLAST-2 antikoerper, CD23 antikoerper, CD23A antikoerper, CLEC4J antikoerper, FCE2 antikoerper, IGEBF antikoerper, Fcer2a antikoerper, Fc fragment of IgE receptor II antikoerper, FCER2 antikoerper, Fcer2 antikoerper

Hintergrund: The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a membrane bound cytokine, in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process