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SCN8A Antikörper (Sodium Channel, Voltage-Gated, Type VIII, alpha) Primary Antibody

SCN8A Reaktivität: Säugetier ISt, IHC Wirt: Maus Monoclonal K87A-10 unconjugated
Pubmed (35 references)
Produktnummer ABIN1304841
$533.50
Zzgl. Versandkosten $45.00
5 mL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 2 bis 6 Werktagen
  • Target Alle SCN8A Antikörper anzeigen
    SCN8A
    Reaktivität
    • 38
    • 30
    • 28
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Säugetier
    Wirt
    • 35
    • 16
    Maus
    Klonalität
    • 36
    • 15
    Monoklonal
    Konjugat
    • 27
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SCN8A Antikörper ist unkonjugiert
    Applikation
    • 26
    • 21
    • 18
    • 13
    • 13
    • 13
    • 13
    • 12
    • 4
    • 3
    • 1
    Immunostaining (ISt), Immunohistochemistry (IHC)
    Produktmerkmale
    Na+ channels
    Aufreinigung
    TC Supernatant: Hybridoma tissue-culture supernatant (5mL) containing 20-40 µg/mL monoclonal antibody (mAb).
    Klon
    K87A-10
    Isotyp
    IgG1
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
  • Wimmer, Harty, Richards, Phillips, Miyazaki, Nukina, Petrou: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).

    Baalman, Marin, Ho, Godoy, Cherian, Robertson, Rasband: "Axon initial segment-associated microglia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 5, pp. 2283-92, (2015) (PubMed).

    Hirono, Ogawa, Misono, Zollinger, Trimmer, Rasband, Misonou: "BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7082-94, (2015) (PubMed).

    King, Manning, Trimmer: "A unique ion channel clustering domain on the axon initial segment of mammalian neurons." in: The Journal of comparative neurology, Vol. 522, Issue 11, pp. 2594-608, (2014) (PubMed).

    Chang, Zollinger, Susuki, Sherman, Makara, Brophy, Cooper, Bennett, Mohler, Rasband: "Glial ankyrins facilitate paranodal axoglial junction assembly." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1673-81, (2014) (PubMed).

    Baalman, Cotton, Rasband, Rasband: "Blast wave exposure impairs memory and decreases axon initial segment length." in: Journal of neurotrauma, Vol. 30, Issue 9, pp. 741-51, (2013) (PubMed).

    Sun, Wagnon, Mahaffey, Briese, Ule, Frankel: "Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice." in: The Journal of physiology, Vol. 591, Issue Pt 1, pp. 241-55, (2013) (PubMed).

    Ruff, Ye, Legasto, Stribbell, Wang, Zhang, Fehlings et al.: "Effects of adult neural precursor-derived myelination on axonal function in the perinatal congenitally dysmyelinated brain: optimizing time of intervention, developing accurate prediction models, and ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 29, pp. 11899-915, (2013) (PubMed).

    Xiao, Bosch, Nerbonne, Ornitz: "FGF14 localization and organization of the axon initial segment." in: Molecular and cellular neurosciences, Vol. 56, pp. 393-403, (2013) (PubMed).

    Buttermore, Piochon, Wallace, Philpot, Hansel, Bhat: "Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 14, pp. 4724-42, (2012) (PubMed).

    Devaux: "Antibodies to gliomedin cause peripheral demyelinating neuropathy and the dismantling of the nodes of Ranvier." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1402-13, (2012) (PubMed).

    Shepherd, Pomicter, Velazco, Henderson, Dupree: "Paranodal reorganization results in the depletion of transverse bands in the aged central nervous system." in: Neurobiology of aging, Vol. 33, Issue 1, pp. 203.e13-24, (2011) (PubMed).

    Binder, Rukavina, Hassani, Weber, Nakatani, Reiff, Parras, Taylor, Rohrer: "Peripheral nervous system progenitors can be reprogrammed to produce myelinating oligodendrocytes and repair brain lesions." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 17, pp. 6379-91, (2011) (PubMed).

    Meehan, MacDermid, Montague, Neuber-Hess, Rose: "Dendrite-derived supernumerary axons on adult axotomized motor neurons possess proteins that are essential for the initiation and propagation of action potentials and synaptic vesicle release." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 18, pp. 6732-40, (2011) (PubMed).

    Duflocq, Chareyre, Giovannini, Couraud, Davenne: "Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B." in: BMC biology, Vol. 9, pp. 66, (2011) (PubMed).

    Brackenbury, Calhoun, Chen, Miyazaki, Nukina, Oyama, Ranscht, Isom: "Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 2283-8, (2010) (PubMed).

    Osorio, Cathala, Meisler, Crest, Magistretti, Delmas: "Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells." in: The Journal of physiology, Vol. 588, Issue Pt 4, pp. 651-70, (2010) (PubMed).

    Liao, Deprez, Maljevic, Pitsch, Claes, Hristova, Jordanova, Ala-Mello, Bellan-Koch, Blazevic, Schubert, Thomas, Petrou, Becker, De Jonghe, Lerche: "Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy." in: Brain : a journal of neurology, Vol. 133, Issue Pt 5, pp. 1403-14, (2010) (PubMed).

    Wimmer, Reid, So, Berkovic, Petrou: "Axon initial segment dysfunction in epilepsy." in: The Journal of physiology, Vol. 588, Issue Pt 11, pp. 1829-40, (2010) (PubMed).

    Lorincz, Nusser: "Molecular identity of dendritic voltage-gated sodium channels." in: Science (New York, N.Y.), Vol. 328, Issue 5980, pp. 906-9, (2010) (PubMed).

  • Target
    SCN8A
    Andere Bezeichnung
    Nav1.6 (SCN8A Produkte)
    Synonyme
    CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4, AI853486, C630029C19Rik, dmu, med, mnd-2, mnd2, nmf2, nmf335, nmf58, nur14, seal, sodium voltage-gated channel alpha subunit 8, sodium channel, voltage-gated, type VIII, alpha, SCN8A, Scn8a
    NCBI Accession
    NP_062139
    Pathways
    Sensory Perception of Sound
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