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SCN2A Antikörper (Sodium Channel, Voltage-Gated, Type II, alpha Subunit) Primary Antibody

SCN2A Reaktivität: Säugetier ISt, IHC, WB Wirt: Maus Monoclonal K69-3 unconjugated
Pubmed (39 references)
Produktnummer ABIN1304839
$460.17
Zzgl. Versandkosten $45.00
5 mL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 2 bis 6 Werktagen
  • Target Alle SCN2A Antikörper anzeigen
    SCN2A
    Reaktivität
    • 31
    • 18
    • 5
    Säugetier
    Wirt
    • 29
    • 7
    • 1
    Maus
    Klonalität
    • 31
    • 6
    Monoklonal
    Konjugat
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SCN2A Antikörper ist unkonjugiert
    Applikation
    • 14
    • 13
    • 13
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunostaining (ISt), Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    Na+ channels
    Aufreinigung
    TC Supernatant: Hybridoma tissue-culture supernatant (5mL) containing 20-40 µg/mL monoclonal antibody (mAb).
    Klon
    K69-3
    Isotyp
    IgG2a
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
  • Gazina, Leaw, Richards, Wimmer, Kim, Aumann, Featherby, Churilov, Hammond, Reid, Petrou: "'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour." in: Human molecular genetics, Vol. 24, Issue 5, pp. 1457-68, (2015) (PubMed).

    Wildburger, Ali, Hsu, Shavkunov, Nenov, Lichti, LeDuc, Mostovenko, Panova-Elektronova, Emmett, Nilsson, Laezza: "Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 5, pp. 1288-300, (2015) (PubMed).

    Hamada, Kole: "Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7272-86, (2015) (PubMed).

    Wimmer, Harty, Richards, Phillips, Miyazaki, Nukina, Petrou: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).

    Liu, Deng, Wang, Zhang, Luo, Yan, Su, Liu: "KCNE2 modulates cardiac L-type Ca(2+) channel." in: Journal of molecular and cellular cardiology, Vol. 72, pp. 208-18, (2014) (PubMed).

    Baek, Rubinstein, Scheuer, Trimmer: "Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures." in: The Journal of biological chemistry, Vol. 289, Issue 22, pp. 15363-73, (2014) (PubMed).

    Wang, Hooks, Sun: "Thorough GABAergic innervation of the entire axon initial segment revealed by an optogenetic 'laserspritzer'." in: The Journal of physiology, Vol. 592, Issue Pt 19, pp. 4257-76, (2014) (PubMed).

    Li, Tian, Scalmani, Frassoni, Mantegazza, Wang, Yang, Wu, Shu: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).

    Tian, Wang, Ke, Guo, Shu: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).

    Martínez-Hernández, Ballesteros-Merino, Fernández-Alacid, Nicolau, Aguado, Luján: "Polarised localisation of the voltage-gated sodium channel Na(v)1.2 in cerebellar granule cells." in: Cerebellum (London, England), Vol. 12, Issue 1, pp. 16-26, (2013) (PubMed).

    He, Liu, Fang, Zhan, Yao, Mei: "Exposure to extremely low-frequency electromagnetic fields modulates Na+ currents in rat cerebellar granule cells through increase of AA/PGE2 and EP receptor-mediated cAMP/PKA pathway." in: PLoS ONE, Vol. 8, Issue 1, pp. e54376, (2013) (PubMed).

    Vega, Avila, Matthews: "Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression." in: Scientific reports, Vol. 3, pp. 2809, (2013) (PubMed).

    Wykes, Kalmbach, Eliava, Waters: "Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice." in: Neurobiology of aging, Vol. 33, Issue 8, pp. 1609-23, (2012) (PubMed).

    Huang, Chu, Hwang, Tsaur: "Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain." in: The Journal of comparative neurology, Vol. 520, Issue 16, pp. 3650-72, (2012) (PubMed).

    Dhaunchak, Becker, Schulman, De Faria, Rajasekharan, Banwell, Colman, Bar-Or: "Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis." in: Annals of neurology, Vol. 71, Issue 5, pp. 601-13, (2012) (PubMed).

    Ahn, Black, Zhao, Tyrrell, Waxman, Dib-Hajj: "Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons." in: Molecular pain, Vol. 7, pp. 32, (2011) (PubMed).

    Lysakowski, Gaboyard-Niay, Calin-Jageman, Chatlani, Price, Eatock: "Molecular microdomains in a sensory terminal, the vestibular calyx ending." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 27, pp. 10101-14, (2011) (PubMed).

    Kaphzan, Buffington, Jung, Rasband, Klann: "Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 48, pp. 17637-48, (2011) (PubMed).

    Kress, Dowling, Eisenman, Mennerick: "Axonal sodium channel distribution shapes the depolarized action potential threshold of dentate granule neurons." in: Hippocampus, Vol. 20, Issue 4, pp. 558-71, (2010) (PubMed).

    Merrick, Kalmar, Snyder, Cusdin, Yu, Sando, Isakson, Jackson, Patel: "The importance of serine 161 in the sodium channel beta3 subunit for modulation of Na(V)1.2 gating." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 4, pp. 743-53, (2010) (PubMed).

  • Target
    SCN2A
    Andere Bezeichnung
    Nav1.2 (SCN2A Produkte)
    Synonyme
    SCN2A2, 6430408L10, A230052E19Rik, Nav1.2, Scn2a, NachII, RII/RIIA, RNSCPIIR, SCN, SCN2A, Scn2a2, ScpII, BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, SCN2A1, sodium voltage-gated channel alpha subunit 2, sodium channel protein type 2 subunit alpha, sodium channel, voltage-gated, type II, alpha, sodium channel, voltage-gated, type II, alpha subunit, SCN2A, LOC100217927, LOC100389294, LOC100484218, Scn2a, LOC478773
    UniProt
    P04775
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