GABRA1 Antikörper (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1)

Produktnummer ABIN1304642

Produktdetails anti-GABRA1 Antikörper

Target: GABRA1

Reaktivität: Säugetier

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GABRA1 Antikörper ist unkonjugiert

Applikation: Immunostaining (ISt), Immunohistochemistry (IHC), Western Blotting (WB)

Produktmerkmale: Receptors

Aufreinigung: TC Supernatant: Hybridoma tissue-culture supernatant (5mL) containing 20-40 µg/mL monoclonal antibody (mAb).

Klon: N95-35

Isotyp: IgG2a

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Referenzen für anti-GABRA1 Antikörper (ABIN1304642)

Kang, Shen, Zhou, Xu, Macdonald: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." in: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).

Arain, Zhou, Ding, Zaidi, Gallagher: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." in: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).

Almeida-Suhett, Prager, Pidoplichko, Figueiredo, Marini, Li, Eiden, Braga: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." in: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).

González, Grabenstatter, Cea-Del Rio, Cruz Del Angel, Carlsen, Laoprasert, White, Huntsman, Brooks-Kayal: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." in: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).

Zhou, Ding, Deel, Ferrick, Emeson, Gallagher: "Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome." in: Neurobiology of disease, Vol. 73C, pp. 407-417, (2014) (PubMed).

King, Manning, Trimmer: "A unique ion channel clustering domain on the axon initial segment of mammalian neurons." in: The Journal of comparative neurology, Vol. 522, Issue 11, pp. 2594-608, (2014) (PubMed).

Mele, Ribeiro, Inácio, Wieloch, Duarte: "GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia." in: Neurobiology of disease, Vol. 65, pp. 220-32, (2014) (PubMed).

Karayannis, Au, Patel, Kruglikov, Markx, Delorme, Héron, Salomon, Glessner, Restituito, Gordon, Rodriguez-Murillo, Roy, Gogos, Rudy, Rice, Karayiorgou, Hakonarson, Keren, Huguet, Bourgeron, Hoeffer et al.: "Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. ..." in: Nature, Vol. 511, Issue 7508, pp. 236-40, (2014) (PubMed).

Ohkawa, Satake, Yokoi, Miyazaki, Ohshita, Sobue, Takashima, Watanabe, Fukata, Fukata: "Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 24, pp. 8151-63, (2014) (PubMed).

Almeida-Suhett, Prager, Pidoplichko, Figueiredo, Marini, Li, Eiden, Braga: "Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury." in: PLoS ONE, Vol. 9, Issue 7, pp. e102627, (2014) (PubMed).

Centanni, Teppen, Risher, Fleming, Moss, Acheson, Mulholland, Pandey, Chandler, Swartzwelder: "Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 11, pp. 2800-8, (2014) (PubMed).

González, Cruz Del Angel, Brooks-Kayal: "Down-regulation of gephyrin and GABAA receptor subunits during epileptogenesis in the CA1 region of hippocampus." in: Epilepsia, Vol. 54, Issue 4, pp. 616-24, (2013) (PubMed).

Hanson, Deng, Hackos, Lo, Lauffer, Steiner, Zhou: "Histone deacetylase 2 cell autonomously suppresses excitatory and enhances inhibitory synaptic function in CA1 pyramidal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 14, pp. 5924-9, (2013) (PubMed).

Zhou, Huang, Ding, Deel, Arain, Murray, Patel, Flanagan, Gallagher: "Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21458-72, (2013) (PubMed).

Chaumont, André, Perrais, Boué-Grabot, Taly, Garret: "Agonist-dependent endocytosis of ?-aminobutyric acid type A (GABAA) receptors revealed by a ?2(R43Q) epilepsy mutation." in: The Journal of biological chemistry, Vol. 288, Issue 39, pp. 28254-65, (2013) (PubMed).

Milenkovic, Vasiljevic, Maurer, Höger, Klausberger, Sieghart: "The parvalbumin-positive interneurons in the mouse dentate gyrus express GABAA receptor subunits ?1, ?2, and ? along their extrasynaptic cell membrane." in: Neuroscience, Vol. 254, pp. 80-96, (2013) (PubMed).

Mihalas, Araki, Huganir, Meffert: "Opposing action of nuclear factor ?B and Polo-like kinases determines a homeostatic end point for excitatory synaptic adaptation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 42, pp. 16490-501, (2013) (PubMed).

Levenga, Krishnamurthy, Rajamohamedsait, Wong, Franke, Cain, Sigurdsson, Hoeffer: "Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments." in: Acta neuropathologica communications, Vol. 1, pp. 34, (2013) (PubMed).

Reid, Pittman, Teskey: "A prolonged experimental febrile seizure results in motor map reorganization in adulthood." in: Neurobiology of disease, Vol. 45, Issue 2, pp. 692-700, (2012) (PubMed).

Antflick, Hampson: "Modulation of glutamate release from parallel fibers by mGlu4 and pre-synaptic GABA(A) receptors." in: Journal of neurochemistry, Vol. 120, Issue 4, pp. 552-63, (2012) (PubMed).

Smith, Muir, Rao, Browarski, Gruenig, Sheehan, Haucke, Kittler: "Stabilization of GABA(A) receptors at endocytic zones is mediated by an AP2 binding motif within the GABA(A) receptor ?3 subunit." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 7, pp. 2485-98, (2012) (PubMed).

Eyre, Renzi, Farrant, Nusser: "Setting the time course of inhibitory synaptic currents by mixing multiple GABA(A) receptor ? subunit isoforms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5853-67, (2012) (PubMed).

Henderson, Pittman, Teskey: "High frequency stimulation alters motor maps, impairs skilled reaching performance and is accompanied by an upregulation of specific GABA, glutamate and NMDA receptor subunits." in: Neuroscience, Vol. 215, pp. 98-113, (2012) (PubMed).

Peters, Muñoz, Sepúlveda, Urrutia, Quiroz, Luza, De Ferrari, Aguayo, Opazo: "Biphasic effects of copper on neurotransmission in rat hippocampal neurons." in: Journal of neurochemistry, Vol. 119, Issue 1, pp. 78-88, (2011) (PubMed).

Mukherjee, Kretschmannova, Gouzer, Maric, Ramsden, Tretter, Harvey, Davies, Triller, Schindelin, Moss: "The residence time of GABA(A)Rs at inhibitory synapses is determined by direct binding of the receptor ?1 subunit to gephyrin." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 41, pp. 14677-87, (2011) (PubMed).

Ding, Feng, Macdonald, Botzolakis, Hu, Gallagher: "GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptors." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26390-405, (2010) (PubMed).

Micheva, Busse, Weiler, ORourke, Smith: "Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers." in: Neuron, Vol. 68, Issue 4, pp. 639-53, (2010) (PubMed).

Details zu GABRA1

Target: GABRA1

Andere Bezeichnung: GABAA R Alpha1 (GABRA1 Produkte)

Synonyme: ECA4, EJM, EJM5, zgc:153566, Gabra-1, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, GABRA1, Gabra1, gabra1, LOC100653509

UniProt: P14867