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LY9 Antikörper (PE)

CD229 Reaktivität: Human FACS Wirt: Maus Monoclonal HLy9-25 PE
Produktnummer ABIN1303129
  • Target Alle LY9 (CD229) Antikörper anzeigen
    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
    Reaktivität
    • 42
    • 6
    • 3
    Human
    Wirt
    • 27
    • 16
    • 2
    Maus
    Klonalität
    • 28
    • 17
    Monoklonal
    Konjugat
    • 20
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY9 Antikörper ist konjugiert mit PE
    Applikation
    • 22
    • 16
    • 13
    • 13
    • 11
    • 10
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    CD299-transfected 300.19 pre-B cell line
    Klon
    HLy9-25
    Isotyp
    IgG1
    Top Product
    Discover our top product CD229 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

    de la Fuente, Tovar, Villamor, Zapater, Pizcueta, Campo, Bosch, Engel: "Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9." in: Blood, Vol. 97, Issue 11, pp. 3513-20, (2001) (PubMed).

  • Target
    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
    Andere Bezeichnung
    CD229 (CD229 Produkte)
    Synonyme
    LY9 antikoerper, CD229 antikoerper, SLAMF3 antikoerper, hly9 antikoerper, mLY9 antikoerper, AI893573 antikoerper, Lgp100 antikoerper, Ly-9 antikoerper, T100 antikoerper, lymphocyte antigen 9 antikoerper, LY9 antikoerper, Ly9 antikoerper
    Hintergrund
    Lymphocyte antigen 9,CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.,SLAMF3, LY9
    Gen-ID
    4063
    UniProt
    Q9HBG7
    Pathways
    BCR Signaling
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