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PDGFRB Antikörper (PE)

PDGFRB Reaktivität: Human FACS Wirt: Maus Monoclonal 18A2 PE
Produktnummer ABIN1303108
  • Target Alle PDGFRB Antikörper anzeigen
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Reaktivität
    • 219
    • 102
    • 82
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 184
    • 41
    • 6
    • 2
    Maus
    Klonalität
    • 171
    • 62
    Monoklonal
    Konjugat
    • 116
    • 13
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Dieser PDGFRB Antikörper ist konjugiert mit PE
    Applikation
    • 162
    • 81
    • 54
    • 54
    • 53
    • 36
    • 33
    • 26
    • 16
    • 13
    • 12
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The monoclonal antibody 18A2 recognizes an extracellular epitope of CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    CD140b-transfected NIH 3T3 cells
    Klon
    18A2
    Isotyp
    IgG1
    Top Product
    Discover our top product PDGFRB Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Fekete, Rojewski, Fürst, Kreja, Ignatius, Dausend, Schrezenmeier: "GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC." in: PLoS ONE, Vol. 7, Issue 8, pp. e43255, (2012) (PubMed).

  • Target
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Abstract
    PDGFRB Produkte
    Synonyme
    AI528809 antikoerper, CD140b antikoerper, PDGFR-1 antikoerper, Pdgfr antikoerper, CD140B antikoerper, IBGC4 antikoerper, JTK12 antikoerper, PDGFR antikoerper, PDGFR1 antikoerper, platelet derived growth factor receptor, beta polypeptide antikoerper, platelet derived growth factor receptor beta antikoerper, Pdgfrb antikoerper, PDGFRB antikoerper
    Hintergrund
    Platelet derived growth factor receptor beta,CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.,PDGFRB, PDGFR1
    Gen-ID
    5159
    UniProt
    Q59F04
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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