PTGDR Antikörper (Extracellular Domain)

Produktnummer ABIN122373

Produktdetails anti-PTGDR Antikörper

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Bindungsspezifität: Extracellular Domain

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGDR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with Prostaglandin D2 Receptor (family: GPCR, subfamily: Prostanoid).

Aufreinigung: Peptide Immunogen Affinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with Formalin Fixed Paraffin Embedded Tissues: 4-7 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min, Remove from heat and let stand at room temperature in buffer for 20 min, Rinse in 1x TBS with Tween (TBST) for 1 min at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline, pH 7.7 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to 70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-PTGDR Antikörper (ABIN122373)

Dash, Ghatak, Topi, Satapathy, Ek, Hellman, Olsson, Mehdawi, Sjölander: "High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model." in: British journal of cancer, Vol. 126, Issue 4, pp. 586-597, (2022) (PubMed).

Details zu PTGDR

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Andere Bezeichnung: PTGDR (PTGDR Produkte)

Synonyme: AS1 antikoerper, ASRT1 antikoerper, DP antikoerper, DP1 antikoerper, PTGDR1 antikoerper, Ptgdr antikoerper, Ptgdr2 antikoerper, PTGDR antikoerper, PGD antikoerper, prostaglandin D2 receptor antikoerper, prostaglandin D receptor antikoerper, PTGDR antikoerper, Ptgdrl antikoerper, Ptgdr antikoerper

Hintergrund: The prostaglandin D2 receptor is a Prostanoid Receptor that binds prostaglandin D2. Studies suggest that this receptor may be involved in vision, mucous secretion, myometrial relaxation, and asthmatic response. Prostaglandin D2 receptor has been reported to be expressed in human small intestine, colon (goblet cells), eye, and eosinophils. ESTs have been isolated from human brain libraries.Synonyms: ASRT1, PGD receptor, PGD2 receptor, Prostaglandin D2 receptor, Prostanoid DP receptor

Gen-ID: 5729

UniProt: Q13258

Pathways: Thromboxane A2 Receptor Signaling