MIF Antikörper (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)) (AA 1-114)

Details for Product anti-MIF Antibody No. ABIN121160, Anbieter: Anmelden zum Anzeigen
Antigen
  • mif
  • Mif
  • gif
  • glif
  • mmif
  • LOC100136498
  • LOC100284350
  • LOC100284546
  • GIF
  • Glif
  • GLIF
  • MMIF
  • macrophage migration inhibitory factor L homeolog
  • macrophage migration inhibitory factor
  • macrophage migration inhibitory factor (glycosylation-inhibiting factor)
  • mif.L
  • mif
  • MIF
  • Mif
  • PHATRDRAFT_49660
  • LOC100136498
  • cl405_1
  • LOC100284546
Epitop
AA 1-114, N-Term
29
28
22
11
10
8
4
3
2
2
2
2
2
2
1
1
1
1
1
Reaktivität
Human
182
64
63
7
6
5
4
3
2
2
2
1
1
Wirt
Maus
109
61
28
16
4
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser MIF Antikörper ist unkonjugiert
17
10
6
4
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
172
115
41
33
29
19
13
11
11
5
4
3
1
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen Recombinant human MIF (1-114 aa) purified from E. coli
Klon 4-00E-004
Isotyp IgG1
Spezifität The antibody recognizes Human MIF. Other species not tested.
Reinigung Protein-G affinity chromatography
Andere Bezeichnung MIF (MIF Antibody Abstract)
Hintergrund The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T-cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.Synonyms: GLIF, Glycosylation-inhibiting factor, MMIF, Macrophage migration inhibitory factor, Phenylpyruvate tautomerase
Gen-ID 4282
UniProt P14174
Pathways Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Applikationshinweise ELISA. Western blot (1/500 - 1/2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-114), (N-Term) antibody (ABIN121160) Western blot analysis.,.The extract of HL-60 was resolved by SDS-PAGE, transferred to...
Allgemeine Veröffentlichungen Richard, Amador Del Valle, Moreau, Milpied, Felice, Daeschler, Harousseau, Richet: "Viridans streptococcal bacteraemia in patients with neutropenia." in: Lancet, Vol. 345, Issue 8965, pp. 1607-9, 1995 (PubMed).

Bernhagen, Mitchell, Calandra, Voelter, Cerami, Bucala: "Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF)." in: Biochemistry, Vol. 33, Issue 47, pp. 14144-55, 1994 (PubMed).

Weiser, Temple, Witek-Giannotti, Remold, Clark, David: "Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 19, pp. 7522-6, 1989 (PubMed).

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