KIR2DL3 Antikörper

Produktnummer ABIN118908

Produktdetails anti-KIR2DL3 Antikörper

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KIR2DL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität: This antibody recognises the CD158b cell surface antigen. This antibody also recognises a 50 kDa molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail.

Aufreinigung: Purified

Immunogen: NK cell clone E57. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3UI myeloma cell line.

Klon: GL183

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide and 0.1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KIR2DL3

Target: KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3))

Andere Bezeichnung: CD158b / KIR2DL3 (KIR2DL3 Produkte)

Synonyme: CD158B2 antikoerper, CD158b antikoerper, GL183 antikoerper, KIR-023GB antikoerper, KIR-K7b antikoerper, KIR-K7c antikoerper, KIRCL23 antikoerper, NKAT antikoerper, NKAT2 antikoerper, NKAT2A antikoerper, NKAT2B antikoerper, p58 antikoerper, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 antikoerper, KIR2DL3 antikoerper

Hintergrund: CD158b is a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). The antigen is a members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.Synonyms: KIRCL23, Killer cell immunoglobulin-like receptor 2DL3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2

Gen-ID: 3804

NCBI Accession: NP_056952

UniProt: P43628

Pathways: Cancer Immune Checkpoints