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CD14 Antikörper

Name: CD14 Antikörper
SKU: ABIN118509
Price: 672.76 EUR
Availability: InStock

CD14 Reaktivität: Human, Affe, Hund, Schwein, Schaf, Kaninchen, Rind (Kuh), Ziege, Cat, Nerz FACS, WB, EIA Wirt: Maus Monoclonal Tük4 unconjugated

Staining of human peripheral blood monocytes probed with Mouse anti Human CD14 (ABIN118509)

FACS

1 image

Produktnummer ABIN118509

Datenblatt (PDF)

Target Alle CD14 Antikörper anzeigen

CD14
Reaktivität
267

55

32

29

29

27

24

24

23

17

17

13

9

8

8

8

7

5

2

2

2

1

1

1
Human, Affe, Hund, Schwein, Schaf, Kaninchen, Rind (Kuh), Ziege, Cat, Nerz
Wirt
224

63

25

3

1
Maus
Passende Sekundärantikörper
Klonalität
252

64
Monoklonal
Konjugat
127

30

24

18

15

8

6

6

5

5

5

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD14 Antikörper ist unkonjugiert
Applikation
223

102

64

59

53

49

22

22

21

14

14

13

7

6

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details)

Species reactivity (expected):Canine, Goat, Cat, Rabbit, Mink, Bovine, Porcine,Sheep, Cynomolgus Monkey, Llama.
Species reactivity (tested):Human.

Aufreinigung

Affinity Chromatography on Protein G.

Klon

Tük4

Isotyp

IgG2a

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CD14 Reaktivität: Human, Non-Human Primate FACS, WB, ELISA, IP Wirt: Maus Monoclonal MEM-18 Biotin

Applikationshinweise

Flow cytometry: 1/50 - 1/200, use 5 μL of suggested working dilution to label 10^6 cells or 100 μL whole blood. ELISA. Western Blot under reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD14

Andere Bezeichnung

CD14 (CD14 Produkte)

Synonyme

CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper

Hintergrund

CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidyl-inositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Gen-ID

9606

UniProt

P08571

Pathways

TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades