ADAM17 Antikörper (AA 226-473)

Produktnummer ABIN1174765

Produktdetails anti-ADAM17 Antikörper

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Bindungsspezifität: AA 226-473

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Verwendungszweck: Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17)

Spezifität: The antibody is a rabbit polyclonal antibody raised against ADAM17. It has been selected for its ability to recognize ADAM17 in immunohistochemical staining and western blotting.

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) corresdonding to Lys226~Arg473 with N-terminal His Tag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-2 μg/mL Immunohistochemistry: 5-20 μg/mL Immunocytochemistry: 5-20 μg/mL Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Andere Bezeichnung: A Disintegrin And Metalloprotease 17 (ADAM17 Produkte)

Synonyme: ADAM18 antikoerper, CD156B antikoerper, CSVP antikoerper, NISBD antikoerper, TACE antikoerper, CD156b antikoerper, Tace antikoerper, adam17 antikoerper, si:dkey-81b15.2 antikoerper, adam18 antikoerper, cd156b antikoerper, csvp antikoerper, tace antikoerper, fc20b01 antikoerper, wu:fc20b01 antikoerper, zgc:63886 antikoerper, ADAM metallopeptidase domain 17 antikoerper, a disintegrin and metallopeptidase domain 17 antikoerper, ADAM metallopeptidase domain 17b antikoerper, ADAM metallopeptidase domain 17 L homeolog antikoerper, ADAM metallopeptidase domain 17a antikoerper, ADAM17 antikoerper, Adam17 antikoerper, adam17b antikoerper, adam17.L antikoerper, adam17a antikoerper

Hintergrund: CD156b, TACE, CSVP, Tumor Necrosis Factor,Alpha,Converting Enzyme, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus