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ANGPTL4 Antikörper

ANGPTL4 Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal Kairos-1 unconjugated
Produktnummer ABIN1169320
  • Target Alle ANGPTL4 Antikörper anzeigen
    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
    Reaktivität
    • 56
    • 27
    • 22
    • 4
    • 4
    • 1
    Human
    Wirt
    • 64
    • 14
    • 2
    Maus
    Klonalität
    • 68
    • 12
    Monoklonal
    Konjugat
    • 55
    • 13
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANGPTL4 Antikörper ist unkonjugiert
    Applikation
    • 65
    • 38
    • 35
    • 9
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    Recognizes the fibrinogen-like domain (FLD) of human ANGPTL4. Detects a band of ~62 kDa and ~35 kDa by Western blot.
    Kreuzreaktivität
    Human
    Kreuzreaktivität (Details)
    Does not cross-react with other ANGPTL family proteins.
    Sterilität
    0.2 μm filtered
    Immunogen
    Recombinant human ANGPTL4.
    Klon
    Kairos-1
    Isotyp
    IgG1
    Top Product
    Discover our top product ANGPTL4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
    Andere Bezeichnung
    ANGPTL4 (ANGPTL4 Produkte)
    Synonyme
    ANGPTL2 antikoerper, ARP4 antikoerper, FIAF antikoerper, HFARP antikoerper, NL2 antikoerper, PGAR antikoerper, pp1158 antikoerper, Arp4 antikoerper, Bk89 antikoerper, Fiaf antikoerper, Hfarp antikoerper, Ng27 antikoerper, Pgar antikoerper, Pgarg antikoerper, Pp1158 antikoerper, ANGPTL4 antikoerper, fiaf antikoerper, im:7144703 antikoerper, si:rp71-39b20.7 antikoerper, angiopoietin like 4 antikoerper, angiopoietin-like 4 antikoerper, ANGPTL4 antikoerper, Angptl4 antikoerper, angptl4 antikoerper
    Hintergrund
    ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.
    UniProt
    Q9BY76
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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