Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
In PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit
12 months
Tussiwand, Rauch, Flück, Rolink: "BAFF-R expression correlates with positive selection of immature B cells." in: European journal of immunology, Vol. 42, Issue 1, pp. 206-16, (2012) (PubMed).
Rauch, Tussiwand, Bosco, Rolink: "Crucial role for BAFF-BAFF-R signaling in the survival and maintenance of mature B cells." in: PLoS ONE, Vol. 4, Issue 5, pp. e5456, (2009) (PubMed).
Target
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.