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CXCL2 Antikörper

CXCL2 Reaktivität: Maus WB, Func, EIA, Neut Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN116268
  • Target Alle CXCL2 Antikörper anzeigen
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    Reaktivität
    • 22
    • 10
    • 9
    • 2
    Maus
    Wirt
    • 34
    • 5
    • 1
    • 1
    Kaninchen
    Klonalität
    • 35
    • 6
    Polyklonal
    Konjugat
    • 28
    • 9
    • 3
    • 1
    Dieser CXCL2 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 20
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA), Neutralization (Neut)
    Spezifität
    This antibody detects Mouse MIP-2. Other species not tested.
    Aufreinigung
    Affinity Chromatography employing immobilized murine mMIP-2 matrix
    Immunogen
    Highly pure (> 98%) E.coli derived recombinant Murine MIP-2
    Top Product
    Discover our top product CXCL2 Primärantikörper
  • Applikationshinweise
    Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity of mMIP-2 (15.00 ng/mL), a concentration of 0.52-0.90 μg/mL of this antibody is required. ELISA: Indirect: Using 100 μL/well antibody solution, a concentration of 0.5 - 2.0 μg/mL isrequired. In conjunction with compatible secondary reagents, it allows the detection of atleast 0.2 - 0.4 ng/well of recombinant mMIP-2. Sandwich: Using 100 μL/well antibody solution, a concentration of 0.5 - 2.0 μg/mL isrequired. In conjunction with Biotinylated Anti-Murine MIP-2 (PP1082B) as a detectionantibody, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant mMIP-2. Western Blot: 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents thedetection limit for recombinant mMIP-2 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
  • Target
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    Andere Bezeichnung
    CXCL2 / MIP2A (CXCL2 Produkte)
    Synonyme
    CINC-2a antikoerper, GRO2 antikoerper, GROb antikoerper, MGSA-b antikoerper, MIP-2a antikoerper, MIP2 antikoerper, MIP2A antikoerper, SCYB2 antikoerper, GRO3 antikoerper, Gro2 antikoerper, MIP-2 antikoerper, Mgsa-b antikoerper, Mip2 antikoerper, Scyb antikoerper, Scyb2 antikoerper, Mip-2 antikoerper, GROB antikoerper, MIP-2alpha antikoerper, C-X-C motif chemokine ligand 2 antikoerper, chemokine (C-X-C motif) ligand 2 antikoerper, CXCL2 antikoerper, Cxcl2 antikoerper
    Hintergrund
    GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60 % amino acid homology to human GRO alpha and GRO gamma.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2
    Gen-ID
    20310
    NCBI Accession
    NP_033166
    UniProt
    P10889
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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