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GDNF Antikörper (Biotin)

GDNF Reaktivität: Human WB, IHC (fro), EIA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN116020
  • Target Alle GDNF Antikörper anzeigen
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Reaktivität
    • 80
    • 43
    • 32
    • 16
    • 16
    • 1
    Human
    Wirt
    • 75
    • 6
    • 4
    • 3
    Kaninchen
    Klonalität
    • 74
    • 13
    • 1
    Polyklonal
    Konjugat
    • 40
    • 10
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GDNF Antikörper ist konjugiert mit Biotin
    Applikation
    • 78
    • 32
    • 26
    • 19
    • 18
    • 13
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Spezifität
    Human Glial Derived Neurotrophic Factor.
    Aufreinigung
    Affinity chromatography.
    Immunogen
    Highly pure (>98%) recombinant hGDNF.
    Top Product
    Discover our top product GDNF Primärantikörper
  • Applikationshinweise
    ELISA: To detect hGDNF by direct ELISA (using 100 ml/well antibody solution) this GDNFantibody can be used at a concentration of 0.15-0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthGDNF. Western Blot: To detect hGDNF by Western Blot analysis this GDNF antibody can be used ata concentration of 0.1-0.2 mg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hGDNF is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Centrifuge vial prior to opening! This product is photosensitive and should be protected from light
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody at 2-8 °C. DO NOT FREEZE!
  • Target
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Andere Bezeichnung
    GDNF (GDNF Produkte)
    Synonyme
    gdnf antikoerper, GDNF antikoerper, AI385739 antikoerper, gdnfa antikoerper, hfb1-gdnf antikoerper, ATF1 antikoerper, ATF2 antikoerper, HFB1-GDNF antikoerper, HSCR3 antikoerper, glial cell derived neurotrophic factor antikoerper, glial cell derived neurotrophic factor a antikoerper, glial cell line derived neurotrophic factor antikoerper, glial cell derived neurotrophic factor L homeolog antikoerper, Gdnf antikoerper, gdnfa antikoerper, GDNF antikoerper, gdnf.L antikoerper
    Hintergrund
    Glial cell line derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor that is a distant member of the TGF beta superfamily. The GDNF gene product is processed to a disulphide-linked homodimer, which is a ligand for the RET protooncogene. GDNF protects and repairs dopamine-containing neurons, which degenerate in Parkinson's disease, and motor neurons, which die in amyotrophic lateral sclerosis. The use of GDNF in the treatment of Parkinson's disease has shown promise in the clinic. Treatment of spinal cord injuries with GDNF has also produced neurological improvement.Synonyms: ATF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor
    Gen-ID
    2668
    NCBI Accession
    NP_000505
    UniProt
    P39905
    Pathways
    RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration
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