NR1I3 Antikörper (C-Term)

Produktnummer ABIN1108490

Produktdetails anti-NR1I3 Antikörper

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1I3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FHGTLRKLQL QEPEYVLLAA MALFSPDRPG VTQRDEIDQL QEEMALTLQS

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Pig, DogSpecies reactivity (tested):Human

Aufreinigung: Purified using Protein A affinity column

Immunogen: The immunogen for anti-NR1I3 antibody: synthetic peptide directed towards the C terminal of human NR1I3.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu NR1I3

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Andere Bezeichnung: NR1I3 / CAR (NR1I3 Produkte)

Synonyme: AA209988 antikoerper, AI551208 antikoerper, CAR antikoerper, CAR-beta antikoerper, Care2 antikoerper, ESTM32 antikoerper, MB67 antikoerper, CAR1 antikoerper, CXR antikoerper, nuclear receptor subfamily 1 group I member 3 antikoerper, nuclear receptor subfamily 1, group I, member 3 antikoerper, NR1I3 antikoerper, Nr1i3 antikoerper

Hintergrund: NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.Synonyms: Constitutive activator of retinoid response, Constitutive androstane receptor, MB67, Nuclear receptor subfamily 1, Orphan nuclear receptor MB67, group I, member 3

Gen-ID: 9970

NCBI Accession: NP_005113

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway