GNRHR Antikörper (Extracellular Domain, N-Term)

Produktnummer ABIN1107411

Produktdetails anti-GNRHR Antikörper

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Bindungsspezifität: AA 1-29, Extracellular Domain, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GNRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Sequenz: MANSASPEQN QHCSAINNSI PLMQGNLPY

Spezifität: This Monoclonal antibody F1G4 reacts with GnRH receptors in the anterior pituitary. F1G4 showed specificity for the synthetic peptide in ELISA and Dot blot.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Mice were immunized with a BSA-conjugated peptide corresponding to amino acids 1-29 of Human GnRH receptor extracellular domain. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability was established by subcloning four times.

Klon: F1G4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GNRHR

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Andere Bezeichnung: GnRH Receptor / GNRHR (GNRHR Produkte)

Synonyme: GNRHR1 antikoerper, GRHR antikoerper, HH7 antikoerper, LHRHR antikoerper, LRHR antikoerper, GNRHR antikoerper, GH1 antikoerper, Lhrhr antikoerper, GNRHR1/III antikoerper, GNRHR2 antikoerper, xgnrhr antikoerper, gnrhr3/ii antikoerper, gnrh-r antikoerper, gonadotropin releasing hormone receptor antikoerper, gonadotropin-releasing hormone receptor antikoerper, GNRHR antikoerper, Gnrhr antikoerper, gnrhr antikoerper, gnrh-r antikoerper

Hintergrund: Gonadotropin Releasing Hormone (GnRH) is down-regulated by hCG and believed to be an autocrine factor that regulates the ovary. The Gonadotropin Releasing Hormone Receptor (GnRHR) is synthesized in the pituitary gland. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinising hormone (LH) as well as follicle-stimulating hormone (FSH). The receptor contains of seven hydrophobic transmembrane domains connected by hydrophillic extracellular, and intracellular loops characteristic of G-protein coupled receptors.Gonadotropin Releasing Hormone (GnRH) is down-regulated by hCG and believed to be an autocrine factor that regulates the ovary. The Gonadotropin Releasing Hormone Receptor (GnRHR) is synthesized in the pituitary gland. Synonyms: GRHR, GnRH-R, Gonadotropin-releasing hormone receptor

Gen-ID: 2798

NCBI Accession: NP_000397

UniProt: P30968