CCNDBP1 Antikörper (Internal Region)

Produktnummer ABIN1105713

Produktdetails anti-CCNDBP1 Antikörper

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Bindungsspezifität: AA 322-333, Internal Region

Reaktivität: Human, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CCNDBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-TKASHVTPQP ED

Spezifität: This antibody recognizes CCNDBP1.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Bovine, Porcine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography

Immunogen: Synthetic peptide (C-TKASHVTPQPED) from the internal region (near C-Terminus) of Human CCNDBP1 (NP_036274.3). Genename: CCNDBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CCNDBP1

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Andere Bezeichnung: CCNDBP1 (CCNDBP1 Produkte)

Synonyme: CCNDBP1 antikoerper, dip1 antikoerper, gcip antikoerper, DIP1 antikoerper, GCIP antikoerper, HHM antikoerper, AU022347 antikoerper, Maid antikoerper, SECC-8 antikoerper, SSEC-8 antikoerper, cyclin D1 binding protein 1 antikoerper, cyclin D-type binding-protein 1 antikoerper, CCNDBP1 antikoerper, ccndbp1 antikoerper, Ccndbp1 antikoerper

Hintergrund: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.Synonyms: Cyclin-D1-binding protein 1, DIP1, GCIP, Grap2 and cyclin-D-interacting protein, HHM, Human homolog of Maid, MAID

Molekulargewicht: 40.3 kDa (NP_036274.3)

Gen-ID: 23582

NCBI Accession: NP_036274