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CTNNB1 Antikörper

CTNNB1 Reaktivität: Human, Ratte, Huhn WB, IF, IHC (fro) Wirt: Maus Monoclonal IMD-110 unconjugated
Produktnummer ABIN1105692
  • Target Alle CTNNB1 Antikörper anzeigen
    CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
    Reaktivität
    • 229
    • 128
    • 113
    • 33
    • 24
    • 24
    • 19
    • 17
    • 12
    • 11
    • 11
    • 9
    • 8
    • 7
    • 6
    • 5
    • 1
    Human, Ratte, Huhn
    Wirt
    • 154
    • 74
    • 3
    • 2
    Maus
    Klonalität
    • 150
    • 83
    Monoklonal
    Konjugat
    • 197
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTNNB1 Antikörper ist unkonjugiert
    Applikation
    • 205
    • 96
    • 95
    • 77
    • 52
    • 48
    • 34
    • 33
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody reacts to Catenin beta-1.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Recombinant chicken beta-catenin
    Klon
    IMD-110
    Isotyp
    IgG1
    Top Product
    Discover our top product CTNNB1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with 1.2 % sodium acetate or neutral PBS
    Konzentration
    0,1 mg/mL
    Buffer
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
    Andere Bezeichnung
    Catenin beta-1 (CTNNB1 Produkte)
    Synonyme
    Jup antikoerper, LOC100217813 antikoerper, CTNNB1 antikoerper, CTNNB antikoerper, Bfc antikoerper, Catnb antikoerper, Mesc antikoerper, ctnnb antikoerper, id:ibd2058 antikoerper, wu:fb73e10 antikoerper, wu:fi81c06 antikoerper, wu:fk25h01 antikoerper, ctnnb1 antikoerper, CHBCAT antikoerper, MRD19 antikoerper, armadillo antikoerper, beta-catenin antikoerper, catenin beta 1 antikoerper, catenin (cadherin associated protein), beta 1 antikoerper, catenin (cadherin-associated protein), beta 1 antikoerper, catenin beta 1 S homeolog antikoerper, catenin beta 1 L homeolog antikoerper, CTNNB1 antikoerper, Ctnnb1 antikoerper, ctnnb1 antikoerper, ctnnb1.S antikoerper, ctnnb1.L antikoerper
    Hintergrund
    Three catenin proteins, alpha, beta and gamma, bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion. Not only associated with E-cadherin, alpha-catenin was also shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. beta-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, is a protein that binds with alpha-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTP associates with catenin/cadherin complexes and may regulate complex signaling.Synonyms: Beta-catenin, CTNNB, CTNNB1
    Gen-ID
    1499
    NCBI Accession
    NP_001091679
    UniProt
    P35222
    Pathways
    WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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