DREAM Antikörper (N-Term)

Produktnummer ABIN1105647

Produktdetails anti-DREAM Antikörper

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Bindungsspezifität: N-Term

Reaktivität: Human, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DREAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: SLLGDLGHTP LS-C

Spezifität: This antibody is expected to recognize Isoform 1 of KCNIP3 (NP_038462.1) only.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human.

Aufreinigung: Purification: Affinity Chromatography

Immunogen: Synthetic peptide with sequence from the N-terminus of Human KCNIP3 (NP_038462.1). Genename: KCNIP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DREAM

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Andere Bezeichnung: Calsenilin (KCNIP3 Produkte)

Synonyme: CSEN antikoerper, DREAM antikoerper, KCHIP3 antikoerper, 4933407H12Rik antikoerper, AI413860 antikoerper, Csen antikoerper, KChIP3 antikoerper, R74849 antikoerper, Dream antikoerper, rKChIP3 antikoerper, csen antikoerper, im:7145308 antikoerper, kcnip3 antikoerper, zgc:73306 antikoerper, KCNIP3 antikoerper, potassium voltage-gated channel interacting protein 3 antikoerper, Kv channel-interacting protein 4 antikoerper, calsenilin antikoerper, Kv channel interacting protein 3, calsenilin antikoerper, Kv channel interacting protein 3b, calsenilin antikoerper, KCNIP3 antikoerper, LOC5568664 antikoerper, CpipJ_CPIJ002549 antikoerper, Tsp_05009 antikoerper, Kcnip3 antikoerper, kcnip3b antikoerper, kcnip3 antikoerper

Hintergrund: KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.Synonyms: A-type potassium channel modulatory protein 3, CSEN, DRE-antagonist modulator, DREAM, KCHIP3, KCNIP3, Kv channel-interacting protein 3

Molekulargewicht: 29.2 kDa according to NP_038462.1.

Gen-ID: 30818

NCBI Accession: NP_001030086