ATP5J Antikörper (Middle Region)

Produktnummer ABIN1105468

Produktdetails anti-ATP5J Antikörper

Target: ATP5J (ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit F6 (ATP5J))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP5J Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects ATPase subunit F6 (mid region).

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: A synthetic peptide mapping at the middle region of human mature ATP5J (CF6) .Remarks: Sequence is different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu ATP5J

Target: ATP5J (ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit F6 (ATP5J))

Andere Bezeichnung: ATPase Subunit F6 (ATP5J Produkte)

Synonyme: zgc:77541 antikoerper, wu:fa66e04 antikoerper, ATP5 antikoerper, ATP5A antikoerper, ATPM antikoerper, CF6 antikoerper, F6 antikoerper, ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 antikoerper, ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6 antikoerper, ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6 L homeolog antikoerper, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 antikoerper, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F antikoerper, atp5j antikoerper, ATP5J antikoerper, atp5j.L antikoerper, Atp5j antikoerper

Hintergrund: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 (ATP5J) is a multisubunit membrane-bound enzyme complex consisting of an F0 segment embedded in the membrane and an F1 segment attached to the F0. It is also a component of mitochondrial ATP synthase which is required for the interactions of the catalytic and proton-translocating segments. Human ATP5J shares 72 % sequence identity with rat ATP5J.This import signal peptide is rich in basic amino acids, devoid of acidic amino acids, and amphiphilic, which allows it to be water-soluble yet capable of passage through the phospholipid membrane bilayers. Moreover, it is circulating and functions as an endogenous vasoconstrictor by inhibiting cytosolic phospholipase A2.Synonyms: ATP synthase, ATP synthase-coupling factor 6 mitochondrial, ATP5A, ATP5J, ATPM, Complex V subunit F6, F1F0 ATPase subunit F6, H+ transporting, mitochondrial F0 complex, subunit F6

Gen-ID: 522

NCBI Accession: NP_001003696

UniProt: P18859

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process