CEACAM1/5 Antikörper
CEACAM1/5
Reaktivität: Human
WB, FACS, ELISA, cELISA, IHC (fro)
Wirt: Maus
Monoclonal
4-3-17
unconjugated
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- Target Alle CEACAM1/5 Produkte
- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
- Reaktivität
- Human
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Wirt
- Maus
-
Klonalität
- Monoklonal
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Konjugat
- Dieser CEACAM1/5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Cell-ELISA (cELISA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Anti-human CEACAM1, 5 (BGP, CEA, CD66a,e)
- Aufreinigung
- Protein G
- Immunogen
- immunisation with extracted protein of CEACAM5
- Klon
- 4-3-17
- Isotyp
- IgG1
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) (N-Term) antibody
CEACAM1/5 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 Western blot: 4 µg/mL
Immunohistology: 1-2 µg/10^6 cells (on cryosections)
For each application a titration should be performed to determine the optimal concentration. - Kommentare
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Synonyms: CD66ae, BGP, CEA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
- Andere Bezeichnung
- CEACAM1,5 (CEACAM1/5 Produkte)
- Synonyme
- CD66e antikoerper, CEA antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, CEACAM5 antikoerper
- Hintergrund
- Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
- UniProt
- P06731, P13688
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