TNFSF4 Antikörper (C-Term)
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- Target Alle TNFSF4 Antikörper anzeigen
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFSF4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- At least two isoforms of TNFSF4 are known to exist, this antibody will detect both isoforms.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal TNFSF4 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TNFSF4.
- Isotyp
- IgG
- Top Product
- Discover our top product TNFSF4 Primärantikörper
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- Applikationshinweise
- TNFSF4 antibody can be used for detection of TNFSF4 by Western blot at 0.5 - 1 μg/mL.
- Kommentare
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(CT) Tumor necrosis factor ligand superfamily 4
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
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- Target
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- Andere Bezeichnung
- TNFSF4 (TNFSF4 Produkte)
- Synonyme
- TNFSF4 antikoerper, OX40L antikoerper, TNFRSF4 antikoerper, CD134L antikoerper, CD252 antikoerper, GP34 antikoerper, OX-40L antikoerper, OX4OL antikoerper, TXGP1 antikoerper, Ath-1 antikoerper, Ath1 antikoerper, Ox40l antikoerper, Txgp1l antikoerper, gp34 antikoerper, TNF superfamily member 4 antikoerper, tumor necrosis factor (ligand) superfamily, member 4 antikoerper, TNFSF4 antikoerper, Tnfsf4 antikoerper
- Hintergrund
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The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Synonyms: Tumor necrosis factor ligand superfamily 4, OX40L, GP34, TXGP1, CD134L, CD252 - Molekulargewicht
- 20 kDa
- Gen-ID
- 7292
- NCBI Accession
- NP_003317
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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