WIPI2 Antikörper (N-Term)

Produktnummer ABIN1077403

Produktdetails anti-WIPI2 Antikörper

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WIPI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: WIPI2 antibody is human and rat reactive. Multiple isoforms of WIPI2 are known to exist. WIPI2 antibody is predicted to not cross-react with WIPI1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal WIPI2 antibody was raised against a 17 amino acid peptide near the amino terminus of human WIPI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WIPI2 antibody can be used for detection of WIPI2 by Western blot at 1 - 2 μg/mL.

Kommentare:

(NT) WD repeat domain phosphoinositide interacting 2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: WIPI2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu WIPI2

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Andere Bezeichnung: WIPI2 (WIPI2 Produkte)

Synonyme: ATG18B antikoerper, Atg21 antikoerper, WIPI-2 antikoerper, 1110018O08Rik antikoerper, 2510001I10Rik antikoerper, WD repeat domain, phosphoinositide interacting 2 L homeolog antikoerper, WD repeat domain, phosphoinositide interacting 2 antikoerper, wipi2.L antikoerper, WIPI2 antikoerper, Wipi2 antikoerper

Hintergrund: WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.
Synonyms: WD repeat domain phosphoinositide interacting 2, WIPI-2, WD40 repeat protein interacting with phosphoinositides 2, WIPI49-like protein 2, ATG18B, ATG21, CGI-50

Molekulargewicht: 50 kDa

Gen-ID: 26100

NCBI Accession: NP_056425