PANX1 Antikörper (N-Term)

Produktnummer ABIN1077400

Produktdetails anti-PANX1 Antikörper

Target: PANX1 (Pannexin 1 (PANX1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PANX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: Two transcript variants encoding different isoforms have been found for this gene.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(NT) Pannexin 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: PANX1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu PANX1

Target: PANX1 (Pannexin 1 (PANX1))

Andere Bezeichnung: PANX1 (PANX1 Produkte)

Synonyme: panx1 antikoerper, zgc:55631 antikoerper, PANX1 antikoerper, px1 antikoerper, mrs1 antikoerper, pannexin1 antikoerper, Pannexin-1 antikoerper, MRS1 antikoerper, PX1 antikoerper, UNQ2529 antikoerper, AI847747 antikoerper, pannexin 1a antikoerper, pannexin 1 antikoerper, Pannexin 1 antikoerper, panx1a antikoerper, PANX1 antikoerper, panx1 antikoerper, Panx1 antikoerper

Hintergrund: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Synonyms: Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028

Molekulargewicht: 47 kDa

Gen-ID: 24145

NCBI Accession: NP_056183