ACSL1 Antikörper

Produktnummer ABIN1077392

Produktdetails anti-ACSL1 Antikörper

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: At least three isoforms of ACSL1 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal ACSL1 antibody was raised against an 18 amino acid peptide near the center of human ACSL1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ACSL1 antibody can be used for detection of ACSL1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(IN) Acyl-CoA synthetase long-chain family member 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: ACSL1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Andere Bezeichnung: ACSL1 (Acsl1 Produkte)

Synonyme: ACS1 antikoerper, FACL1 antikoerper, FACL2 antikoerper, LACS antikoerper, LACS1 antikoerper, LACS2 antikoerper, Acas antikoerper, Acas1 antikoerper, Acs antikoerper, FACS antikoerper, Facl2 antikoerper, ACS antikoerper, COAA antikoerper, zgc:110081 antikoerper, CER8 antikoerper, ECERIFERUM 8 antikoerper, LONG-CHAIN ACYL-COA SYNTHASE 1 antikoerper, T8I13.8 antikoerper, F13F21.14 antikoerper, F13F21_14 antikoerper, LATERAL ROOT DEVELOPMENT 2 antikoerper, LRD2 antikoerper, long-chain acyl-CoA synthetase 2 antikoerper, acyl-CoA synthetase long chain family member 1 antikoerper, acyl-CoA synthetase long-chain family member 1 antikoerper, acyl-CoA synthetase long chain family member 1a antikoerper, AMP-dependent synthetase and ligase family protein antikoerper, long-chain acyl-CoA synthetase 2 antikoerper, ACSL1 antikoerper, Acsl1 antikoerper, acsl1a antikoerper, LACS1 antikoerper, LACS2 antikoerper

Hintergrund: Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ASCL1 is the major acyl-CoA enzyme in the heart, providing 60-90% of heart ATP. Loss of ASCL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy.
Synonyms: Acyl-CoA synthetase long-chain family member 1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2, palmitoyl-CoA ligase 1

Molekulargewicht: 77 kDa

Gen-ID: 2180

NCBI Accession: NP_001986

Pathways: Regulation of Lipid Metabolism by PPARalpha