PLA1A Antikörper (C-Term)

Produktnummer ABIN1077384

Produktdetails anti-PLA1A Antikörper

Target: PLA1A (Phospholipase A1 Member A (PLA1A))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: At least three isoforms of PLA1A are known to exist, this antibody will detect all three isoforms.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: PLA1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human PLA1A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PLA1A antibody can be used for detection of PLA1A by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(CT) Phospholipase A1 member A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: PLA1A antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu PLA1A

Target: PLA1A (Phospholipase A1 Member A (PLA1A))

Andere Bezeichnung: PLA1A (PLA1A Produkte)

Synonyme: PS-PLA1 antikoerper, PSPLA1 antikoerper, AA986889 antikoerper, Ps-pla1 antikoerper, Pspla1 antikoerper, wu:fi26h09 antikoerper, zgc:77160 antikoerper, AH antikoerper, ARWH2 antikoerper, LAH2 antikoerper, LPDLR antikoerper, PLA1B antikoerper, mPA-PLA1 antikoerper, phospholipase A1 member A antikoerper, lipase H antikoerper, PLA1A antikoerper, Pla1a antikoerper, pla1a antikoerper, CpipJ_CPIJ002492 antikoerper, CpipJ_CPIJ007883 antikoerper, LIPH antikoerper

Hintergrund: PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.
Synonyms: Phospholipase A1 member A, phosphatidylserine-specific phospholipase A1, PS-PLA1

Molekulargewicht: 50 kDa

Gen-ID: 51365

NCBI Accession: NP_056984