SFRP1 Antikörper (AA 12)

Produktnummer ABIN1043877

Produktdetails anti-SFRP1 Antikörper

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Bindungsspezifität: AA 12

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: SFRP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region of human Sfrp1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 37 kDa in size corresponding to Sfrp1 by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-SFRP1 Antikörper (ABIN1043877)

Huang, Zhang, Teng, Lin, Zheng, Yang, Han: "Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma." in: BMC cancer, Vol. 7, pp. 126, (2007) (PubMed).

Garcia-Hoyos, Cantalapiedra, Arroyo, Esteve, Rodríguez, Riveiro, Trujillo, Ramos, Bovolenta, Ayuso: "Evaluation of SFRP1 as a candidate for human retinal dystrophies." in: Molecular vision, Vol. 10, pp. 426-31, (2004) (PubMed).

Han, Amar: "Secreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosis." in: The Journal of biological chemistry, Vol. 279, Issue 4, pp. 2832-40, (2004) (PubMed).

Details zu SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1 (SFRP1 Produkte)

Synonyme: FRP antikoerper, FRP-1 antikoerper, FRP1 antikoerper, FrzA antikoerper, SARP2 antikoerper, 2210415K03Rik antikoerper, AW011917 antikoerper, AW107218 antikoerper, AW742929 antikoerper, sFRP-1 antikoerper, CSFRP1 antikoerper, SFRP1 antikoerper, XfrzA antikoerper, frp antikoerper, frp-1 antikoerper, frp1 antikoerper, frzA antikoerper, sarp2 antikoerper, sfrp1 antikoerper, LOC100231868 antikoerper, Srfp1a antikoerper, wu:fd19b09 antikoerper, secreted frizzled related protein 1 antikoerper, secreted frizzled-related protein 1 antikoerper, Secreted frizzled-related protein 1 antikoerper, secreted frizzled-related protein 1a antikoerper, secreted frizzled-related protein 1b antikoerper, SFRP1 antikoerper, Sfrp1 antikoerper, sfrp1 antikoerper, sfrp1a antikoerper, sfrp1b antikoerper

Hintergrund: Anti-SFRP1 is a Stem Cell Antibody. SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
Synonyms: Frizzled related protein 1 antibody, FRP 1 antibody, FRP antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP2 antibody, Secreted Apoptosis-related Protein 2 antibody

Gen-ID: 6422, 56117838

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation