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VEGF Antikörper (Biotin)

VEGF Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1043812
  • Target Alle VEGF Antikörper anzeigen
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    Reaktivität
    • 79
    • 47
    • 35
    • 18
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 52
    • 26
    • 12
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 58
    • 34
    • 1
    Polyklonal
    Konjugat
    • 43
    • 12
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VEGF Antikörper ist konjugiert mit Biotin
    Applikation
    • 79
    • 54
    • 23
    • 20
    • 15
    • 14
    • 12
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Biotin Conjugated VEGF Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human VEGF-165 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
    Produktmerkmale
    VEGF (Vascular Endothelial Growth Factor A) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF 165 and VEGF 121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF 189 and VEGF 206) remain cell associated. The sequence of this isoform differs from the canonical sequence as follows: 141-141: K -> N and 142-182: missing. This isoform is often found as a disulfide linked homodimer.
    Immunogen
    VEGF Antibody Biotin Conjugated was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human VEGF-165 protein.
    Immunogen Type: RecombinantProtein
    Isotyp
    IgG
    Top Product
    Discover our top product VEGF Primärantikörper
  • Applikationshinweise
    VEGF conjugated antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 22 kDa in size corresponding to monomeric human VEGF-165 protein by western blotting in the appropriate cell lysate or extract.
    Kommentare

    Gene Name: VEGFA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Rigopoulos, Tsiambas, Lazaris, Kavantzas, Papazachariou, Kravvaritis, Tsounis, Koliopoulou, Athanasiou, Karameris, Manaios, Sergentanis, Patsouris: "Deregulation of EGFR/VEGF/HIF-1a signaling pathway in colon adenocarcinoma based on tissue microarrays analysis." in: Journal of B.U.ON. : official journal of the Balkan Union of Oncology, Vol. 15, Issue 1, pp. 107-15, (2010) (PubMed).

    Sun, Hu, Huang, Chu, Zhang, She, Chen: "Brain-derived neurotrophic factor induces proliferation, migration, and VEGF secretion in human multiple myeloma cells via activation of MEK-ERK and PI3K/AKT signaling." in: Tumour biology, Vol. 31, Issue 2, pp. 121-8, (2010) (PubMed).

    Huez, Bornes, Bresson, Créancier, Prats: "New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation." in: Molecular endocrinology (Baltimore, Md.), Vol. 15, Issue 12, pp. 2197-210, (2001) (PubMed).

  • Target
    VEGF (Vascular Endothelial Growth Factor (VEGF))
    Andere Bezeichnung
    VEGF (VEGF Produkte)
    Synonyme
    MVCD1 antikoerper, VEGF antikoerper, VPF antikoerper, Vegf antikoerper, Vegf120 antikoerper, Vegf164 antikoerper, Vegf188 antikoerper, Vpf antikoerper, VEGF-A antikoerper, VEGF164 antikoerper, eVEGF120 antikoerper, eVEGF164 antikoerper, vegf-a antikoerper, vegf antikoerper, vascular endothelial growth factor A antikoerper, vascular endothelial growth factor A L homeolog antikoerper, vascular endothelial growth factor antikoerper, vascular endothelial growth factor precursor antikoerper, VEGFA antikoerper, Vegfa antikoerper, vegfa.L antikoerper, VEGF antikoerper, vegf antikoerper
    Hintergrund
    VEGF (Vascular Endothelial Growth Factor A) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF 165 and VEGF 121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF 189 and VEGF 206) remain cell associated. The sequence of this isoform differs from the canonical sequence as follows: 141-141: K → N and 142-182: missing. This isoform is often found as a disulfide linked homodimer.
    Synonyms: Vascular endothelial growth factor A; VEGF-A; VEGF-165, VEGF165, VEGF isoform L, Vascular permeability factor; VPF
    Gen-ID
    7422
    NCBI Accession
    NP_001165097
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