anti-Human STRADA Antikörper für Enzyme Immunoassay

Recommended STRADA Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
STE20-Related Kinase Adaptor alpha (STRADA) Antikörper
  • fj99g05
  • zgc:56109
  • wu:fj99g05
  • lyk5
  • LYK5
  • NY-BR-96
  • PMSE
  • STRAD
  • Stlk
  • Lyk5
  • 2610019A05Rik
  • 6030402H20Rik
  • AI480680
  • E130112C09Rik
  • STE20-related kinase adaptor alpha
  • ste20-related kinase adaptor alpha
  • STRADA
  • strada
  • Strada
Epitop
N-Term
20
17
10
9
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human
104
41
19
7
3
2
2
2
2
1
1
Wirt
Kaninchen
99
5
Klonalität
Polyklonal
Konjugat
Dieser STRADA Antikörper ist unkonjugiert
7
7
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
90
52
13
13
12
8
8
4
4
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN359296
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN359297 EIA WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen STE20-Related Kinase Adaptor alpha (STRADA) Antikörper
Epitop N-Term
(20), (17), (10), (9), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(104), (41), (19), (7), (3), (2), (2), (2), (2), (1), (1)
Wirt Kaninchen
(99), (5)
Klonalität
Polyklonal
Konjugat Dieser STRADA Antikörper ist unkonjugiert
(7), (7), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(90), (52), (13), (13), (12), (8), (8), (4), (4), (1), (1)
Pubmed 1 Publikation vorhanden
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Produktdetails anti-STRADA Antikörper

Target Details STRADA Anwendungsinformationen Handhabung Referenzen für anti-STRADA Antikörper (ABIN359296) Bilder
Spezifität This antibody reacts to LYK5.
Reinigung Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LYK5.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details STRADA

Produktdetails anti-STRADA Antikörper Anwendungsinformationen Handhabung Referenzen für anti-STRADA Antikörper (ABIN359296) Bilder zurück nach oben
Antigen
Andere Bezeichnung STRAD alpha / LYK5 (STRADA Antibody Abstract)
Hintergrund LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.Synonyms: NY-BR-96, STE20-related adapter protein, STE20-related kinase adapter protein alpha, STRAD, STRADA
Gen-ID 92335, 9606
UniProt Q7RTN6
Pathways AMPK Signaling

Anwendungsinformationen

Produktdetails anti-STRADA Antikörper Target Details STRADA Handhabung Referenzen für anti-STRADA Antikörper (ABIN359296) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-STRADA Antikörper Target Details STRADA Anwendungsinformationen Referenzen für anti-STRADA Antikörper (ABIN359296) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-STRADA Antikörper (ABIN359296)

Produktdetails anti-STRADA Antikörper Target Details STRADA Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Baas, Boudeau, Sapkota, Smit, Medema, Morrice, Alessi, Clevers: "Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD." in: The EMBO journal, Vol. 22, Issue 12, pp. 3062-72, 2003

Bilder

Produktdetails anti-STRADA Antikörper Target Details STRADA Anwendungsinformationen Handhabung Referenzen für anti-STRADA Antikörper (ABIN359296) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-STE20-Related Kinase Adaptor alpha (STRADA) (N-Term) antibody (ABIN359296) The anti-LYK5 Pab is used in Western blot to detect LYK5 in mouse brain tissue lysate