anti-Pferd SREBF1 Antikörper für Western Blotting

Recommended SREBF1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) Antikörper
  • SREBP-1c
  • SREBP1
  • bHLHd1
  • ADD-1
  • ADD1
  • D630008H06
  • SREBP-1
  • SREBP-1a
  • SREBP1c
  • Srebp1
  • SCREBP1
  • SREBP-1C
  • SREBF1
  • srebp1
  • sterol regulatory element binding transcription factor 1
  • sterol regulatory element binding transcription factor 1 L homeolog
  • sterol regulatory element binding protein-1
  • Sterol regulatory element Binding Protein
  • SREBF1
  • Srebf1
  • srebf1.L
  • SREBP-1
  • srebf1
  • sbp-1
Epitop
N-Term
16
15
14
14
12
10
7
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
146
85
71
37
21
17
17
17
16
12
5
3
2
2
1
1
1
1
Wirt
Kaninchen
117
37
Klonalität
Polyklonal
Konjugat
Dieser SREBF1 Antikörper ist unkonjugiert
7
6
6
5
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
Applikation
Western Blotting (WB)
148
46
40
19
16
15
8
3
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2780569
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2534187 ABIN2792233 IHC WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN959064 IHC (p) WB Rabbit IgG AA 461-510 Anmelden zum Anzeigen Polyclonal 0
1 ABIN468354 WB Rabbit AA 35-84 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) Antikörper
Epitop N-Term
(16), (15), (14), (14), (12), (10), (7), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(146), (85), (71), (37), (21), (17), (17), (17), (16), (12), (5), (3), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(117), (37)
Klonalität
Polyklonal
Konjugat Dieser SREBF1 Antikörper ist unkonjugiert
(7), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Western Blotting (WB)
(148), (46), (40), (19), (16), (15), (8), (3), (3), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SREBF1 Antikörper

Target Details SREBF1 Anwendungsinformationen Handhabung Referenzen für anti-SREBF1 Antikörper (ABIN2780569) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984411.
Sequenz AGRGRANGLD APRAGADRGA MDCTFEDMLQ LINNQDSDFP GLFDPPYAGS
Homologie Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against SREBF1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SREBF1

Target Details SREBF1

Produktdetails anti-SREBF1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-SREBF1 Antikörper (ABIN2780569) Bilder zurück nach oben
Antigen
Andere Bezeichnung SREBF1 (SREBF1 Antibody Abstract)
Hintergrund SREBF1is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17.This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: SREBP1, bHLHd1, SREBP-1c
Protein Interaction Partner: UBC, ERLIN2, FBXW7, SMARCD3, HSP90AA1, SUMO1, ATXN1L, INSIG2, SCAP, ATXN1, LMNA, INSIG1, EGF, SREBF2, SREBF1, ZBTB7A, ZBTB7C, SUMO2, MED6, MED13, MED12, MED24, MED26, MED17, MED23, MED14, USF1, MED1, GSK3B, CREBBP, CDK8, MED25, MED15, MED7, MED21, SIRT1,
Protein Size: 1177
Molekulargewicht 125 kDa
Gen-ID 6720
NCBI Accession NM_001005291, NP_001005291
Pathways AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha

Anwendungsinformationen

Produktdetails anti-SREBF1 Antikörper Target Details SREBF1 Handhabung Referenzen für anti-SREBF1 Antikörper (ABIN2780569) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1177 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SREBF1 Antikörper Target Details SREBF1 Anwendungsinformationen Referenzen für anti-SREBF1 Antikörper (ABIN2780569) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SREBF1 Antikörper (ABIN2780569)

Produktdetails anti-SREBF1 Antikörper Target Details SREBF1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Arazi, Genvigir, Willrich, Hirata, Dorea, Bernik, Hirata: "Atorvastatin effects on SREBF1a and SCAP gene expression in mononuclear cells and its relation with lowering-lipids response." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 393, Issue 2, pp. 119-24, 2008

Bilder

Produktdetails anti-SREBF1 Antikörper Target Details SREBF1 Anwendungsinformationen Handhabung Referenzen für anti-SREBF1 Antikörper (ABIN2780569) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (N-Term) antibody (ABIN2780569) WB Suggested Anti-SREBF1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: