Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
mechanisms of interaction with flagellin (zeige FliC Proteine) and profilin (zeige PFN1 Proteine)
Data show that TLR11 expression is induced in astrocytes, neurons, and microglia in the immune response to T. gondii infection
TLR11 mediates innate immune function of male germ cells in response to T. gondii profilin (zeige PFN1 Proteine) and uropathogenic escherichia coli stimulations.
Biochemical experiments revealed that TLR11 and TLR12 (zeige Tlr12 Proteine) directly bind to Toxoplasma gondii profilin (zeige PFN1 Proteine) and are capable of forming a heterodimer complex.
Selective elimination of neutrophils in TLR11-deficient mice infected with Toxoplasma gondii results in acute susceptibility similar to that observed in IFN-gamma (zeige IFNG Proteine)-deficient mice.
While parasite RNA and DNA activate innate immune responses via TLR7 (zeige TLR7 Proteine) and TLR9 (zeige TLR9 Proteine), TLR11 and TLR12 (zeige Tlr12 Proteine) heterodimers are required for sensing and responding to Toxoplasma profilin (zeige PFN1 Proteine) infection.
a potentially important role for TLR11 in preventing murine intestinal infection and modulating antigen transportation in the gut (zeige GUSB Proteine) and imply an important role for various TLRs in cooperation with tight control of pathogens penetrating into Peyer patches.
association with UNC93B1 and the intracellular localization of TLRs are not unique features of nucleic acid-sensing TLRs but is also essential for TLR11-dependent recognition of T. gondii profilin (zeige PFN1 Proteine) and for host protection against this parasite
Data demonstrate that transcription of the Tlr11 gene is regulated through epithelium-specific transcription factors and IRF-8 (zeige IRF8 Proteine).
displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells; mice lacking TLR11 are highly susceptible to infection of the kidneys by uropathogenic bacteria
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).