anti-Katze MICA Antikörper für Immunoprecipitation

Recommended MICA Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
MHC Class I Polypeptide-Related Sequence A (MICA) Antikörper
  • MIC-A
  • PERB11.1
  • Ica
  • mICA
  • MHC class I polypeptide-related sequence A
  • RIKEN cDNA 1300017J02 gene
  • MICA
  • 1300017J02Rik
Reaktivität
Human, Non-Human Primate, Rind (Kuh), Katze
147
13
11
9
7
6
2
Wirt
Maus
78
66
1
Klonalität
Monoklonal
Konjugat
Dieser MICA Antikörper ist konjugiert mit PE
11
6
5
5
4
4
3
3
3
3
3
1
1
Applikation
ELISA, Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Western Blotting (WB)
84
83
37
28
22
15
13
11
5
5
5
4
4
4
4
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN125724
$ 493.35
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1774789 ELISA FACS Func ICC IHC (f) IP WB Mouse IgG2a Anmelden zum Anzeigen W6-32 9
1 ABIN94333 ELISA FACS Func ICC IHC (f) IP WB Biotin Mouse IgG2a Anmelden zum Anzeigen W6-32 9
1 ABIN94334 ELISA FACS Func ICC IHC (f) IP WB FITC Mouse IgG2a Anmelden zum Anzeigen W6-32 9
1 ABIN2749085 Func IHC (f) ICC FACS IP ELISA WB Mouse IgG2a Anmelden zum Anzeigen W6-32 9
1 ABIN3040373 ELISA FACS IF/ICC IHC IP WB Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN3038583 ELISA FACS IF/ICC IHC IP WB Biotin Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN3040375 ELISA FACS IF/ICC IHC IP WB FITC Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN3040374 ELISA FACS IF/ICC IHC IP WB PE Mouse IgG2a Anmelden zum Anzeigen 0
1 ABIN3038577 ELISA FACS IF/ICC IHC IP WB Mouse IgG2a Anmelden zum Anzeigen 0

General

Antigen MHC Class I Polypeptide-Related Sequence A (MICA) Antikörper
Reaktivität Human, Non-Human Primate, Rind (Kuh), Katze
(147), (13), (11), (9), (7), (6), (2)
Wirt Maus
(78), (66), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser MICA Antikörper ist konjugiert mit PE
(11), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (1), (1)
Applikation ELISA, Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Western Blotting (WB)
(84), (83), (37), (28), (22), (15), (13), (11), (5), (5), (5), (4), (4), (4), (4), (1), (1), (1), (1)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MICA Antikörper

Target Details MICA Anwendungsinformationen Handhabung Referenzen für anti-MICA Antikörper (ABIN125724) Bilder
Spezifität The antibody W6/32 recognises MHC Class I molecules (MHC Class Ia) that are expressed on the surface of all human nucleated cell types.
The antibody W6/32 is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders.
This antibody W6/32 is also suitable as a positive control for HLA tissue typing and crossmatching.
Keine Kreuzreaktivität Kaninchen
Produktmerkmale The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Immunogen Membrane of human tonsil cells
Klon W6-32
Isotyp IgG2a

Target Details MICA

Produktdetails anti-MICA Antikörper Anwendungsinformationen Handhabung Referenzen für anti-MICA Antikörper (ABIN125724) Bilder zurück nach oben
Antigen
Andere Bezeichnung MICA (MICA Antibody Abstract)
Hintergrund HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Pathways Activation of Innate immune Response, Transition Metal Ion Homeostasis

Anwendungsinformationen

Produktdetails anti-MICA Antikörper Target Details MICA Handhabung Referenzen für anti-MICA Antikörper (ABIN125724) Bilder zurück nach oben
Applikations-hinweise The reagent is designed for Flow Cytometry analysis.Suggested working dilution is 1:50. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MICA Antikörper Target Details MICA Anwendungsinformationen Referenzen für anti-MICA Antikörper (ABIN125724) Bilder zurück nach oben
Konzentration 0.1 mg/mL
Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Do not freeze.
Avoid prolonged exposure to light.
Lagerung 4 °C
Informationen zur Lagerung Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

Referenzen für anti-MICA Antikörper (ABIN125724)

Produktdetails anti-MICA Antikörper Target Details MICA Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Tyciakova, Matuskova, Bohovic, Polakova, Toro, Skolekova, Kucerova: "Genetically engineered mesenchymal stromal cells producing TNF? have tumour suppressing effect on human melanoma xenograft." in: The journal of gene medicine, 2015

Le Discorde, Moreau, Sabatier, Legeais, Carosella: "Expression of HLA-G in human cornea, an immune-privileged tissue." in: Human immunology, Vol. 64, Issue 11, pp. 1039-44, 2003

Tran, Ivanyi, Hilgert, Brdicka, Pla, Breur, Flieger, Ivasková, Horejsí: "The epitope recognized by pan-HLA class I-reactive monoclonal antibody W6/32 and its relationship to unusual stability of the HLA-B27/beta2-microglobulin complex." in: Immunogenetics, Vol. 53, Issue 6, pp. 440-6, 2001

Ladasky, Shum, Canavez, Seuánez, Parham: "Residue 3 of beta2-microglobulin affects binding of class I MHC molecules by the W6/32 antibody." in: Immunogenetics, Vol. 49, Issue 4, pp. 312-20, 1999

Shields, Ribaudo: "Mapping of the monoclonal antibody W6/32: sensitivity to the amino terminus of beta2-microglobulin." in: Tissue antigens, Vol. 51, Issue 5, pp. 567-70, 1998

Jacobsen, Aasted, Broe, Petersen: "Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species." in: Veterinary immunology and immunopathology, Vol. 39, Issue 4, pp. 461-6, 1994

Stern, Beresford, Friedman, Stevens, Risk, Johnson: "Class I-like MHC molecules expressed by baboon placental syncytiotrophoblast." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 4, pp. 1088-91, 1987

Neefjes, Hensen, de Kroon, Ploegh: "A biochemical characterization of feline MHC products: unusually high expression of class II antigens on peripheral blood lymphocytes." in: Immunogenetics, Vol. 23, Issue 5, pp. 341-7, 1986

Brodsky, Parham: "Evolution of HLA antigenic determinants: species cross-reactions of monoclonal antibodies." in: Immunogenetics, Vol. 15, Issue 2, pp. 151-66, 1982

Barnstable, Bodmer, Brown, Galfre, Milstein, Williams, Ziegler: "Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis." in: Cell, Vol. 14, Issue 1, pp. 9-20, 1978

Bilder

Produktdetails anti-MICA Antikörper Target Details MICA Anwendungsinformationen Handhabung Referenzen für anti-MICA Antikörper (ABIN125724) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibody (PE) (ABIN125724) Surface staining of human peripheral blood cells with anti-HLA-class I(W6/32) Alexa F...