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Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validierenRelevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
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-12.929095 | ABIN4334539 | FACS ICC IF IHC IHC (p) WB | DyLight 405 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334549 | FACS ICC IF IHC IHC (p) WB | Alexa Fluor 647 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334538 | FACS ICC IF IHC IHC (p) WB | DyLight 350 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334544 | FACS ICC IF IHC IHC (p) WB | DyLight 488 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334546 | FACS ICC IF IHC IHC (p) WB | DyLight 680 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334550 | FACS ICC IF IHC IHC (p) WB | Alexa Fluor 700 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334543 | FACS ICC IF IHC IHC (p) WB | DyLight 755 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334547 | FACS ICC IF IHC IHC (p) WB | Alexa Fluor 405 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN4334548 | FACS ICC IF IHC IHC (p) WB | Alexa Fluor 488 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN5947286 | FACS ICC IF IHC IHC (p) | Janelia Fluor® 549 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 | ||
-12.929095 | ABIN5947287 | FACS ICC IF IHC IHC (p) | Janelia Fluor® 646 | Mouse | IgG1 | Anmelden zum Anzeigen | H10E4C9F | 0 |
General |
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Antigen | Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) Antikörper |
Reaktivität | Huhn, Human, Maus, Kaninchen, Ratte (Rattus), Schaf Alternativen |
Wirt | Maus Alternativen |
Klonalität (Klon) | |
Konjugat | Dieser NR3C2 Antikörper ist unkonjugiert Alternativen |
Applikation |
Blocking Peptide (BP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Western Blotting (WB)
Alternativen
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1 Publikation vorhanden |
Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-NR3C2 AntikörperTarget Details NR3C2 Anwendungsinformationen Handhabung Referenzen für anti-NR3C2 Antikörper (ABIN152721) Bilder |
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Spezifität | Detects mineralocorticoid receptor (MR). |
Reinigung | Protein A purified |
Immunogen | Aldosterone-3 |
Klon | H10E4C9F |
Isotyp | IgG1 |
Plasmids, Primers & others | |
Target Details NR3C2Produktdetails anti-NR3C2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-NR3C2 Antikörper (ABIN152721) Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | Mineralocorticoid receptor (NR3C2 Antibody Abstract) |
Hintergrund | Gene Symbol: NR3C2 |
Gen-ID | 4306 |
UniProt | P08235 |
Pathways | ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway |
AnwendungsinformationenProduktdetails anti-NR3C2 Antikörper Target Details NR3C2 Handhabung Referenzen für anti-NR3C2 Antikörper (ABIN152721) Bilder zurück nach oben |
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Applikations-hinweise | Western Blot 1:1000, Flow Cytometry 1:20, Immunohistochemistry 1:100, Immunocytochemistry/Immunofluorescence 1:100 - 1:200, Immunohistochemistry-Paraffin 1:100, Blocking/Neutralizing 50 - 200 Molar excessUseful in IHC, ICC, and WB. Not suitable for IP. WB: Detects an approx. 116 kDa protein representing MR in rat heart homogenate. IHC: Staining of MR in rabbit atrium with NB300-562 results in strong staining of myocytes and endothelial cells. IHC: Staining with NB300-562 is blocked by pre-incubating the sample with aldosterone. NB300-562 can also be used in formalin-fixed, paraffin-embedded sections. Due to the extremely low levels of MR expressed in native tissues, it is recommended that enhanced detection systems be used for WBting such as enhanced chemiluminescence. NB300-562 blocks the binding of aldosterone since it is directed against the steroid binding domain of the mineralocorticoid receptor. |
Kommentare |
The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo. |
Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-NR3C2 Antikörper Target Details NR3C2 Anwendungsinformationen Referenzen für anti-NR3C2 Antikörper (ABIN152721) Bilder zurück nach oben |
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Format | Liquid |
Konzentration | 1.4 mg/mL |
Buffer |
PBS Buffer contains: 0.05 % Sodium Azide |
Konservierungs-mittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handhabung | Avoid freeze-thaw cycles |
Lagerung | -20 °C |
Informationen zur Lagerung | Store at -20°C. Avoid freeze-thaw cycles. |
Referenzen für anti-NR3C2 Antikörper (ABIN152721)Produktdetails anti-NR3C2 Antikörper Target Details NR3C2 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Produkt verwendet in: |
Leite-Dellova, Szriber, Merighe, Polidoro, Rebouças, Oliveira-Souza, de Mello-Aires: "Signaling pathways involved in the rapid biphasic effect of aldosterone on Na+/H+ exchanger in rat proximal tubule cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 182, pp. 87-94, 2018 |
BilderProduktdetails anti-NR3C2 Antikörper Target Details NR3C2 Anwendungsinformationen Handhabung Referenzen für anti-NR3C2 Antikörper (ABIN152721) zurück nach oben |
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Bilder des Herstellers |
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