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anti-Human Cathepsin G Antikörper:
anti-Mouse (Murine) Cathepsin G Antikörper:
anti-Rat (Rattus) Cathepsin G Antikörper:
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CatG can be used as a novel marker to distinguish different NK cell subsets and MARS116 is applicable to determine cell surface CatG activity by flow cytometry.
Results provide evidence that cathepsin G (GC) activates IGF-1R (zeige IGF1R Antikörper) by stimulating IGF-1 (zeige IGF1 Antikörper) release from MCF-7 cells, and that IGF-1R (zeige IGF1R Antikörper) activation is required for CG-induced cell aggregation.
Cleavage of the alarmins by Human mast cell chymase (zeige CMA1 Antikörper) and human neutrophil cathepsin G suggests a function in regulating excessive inflammation.
Data show that lactoferrin (LF (zeige LTF Antikörper)) increases the catalytic activity of cathepsin G (CatG) at physiological concentration.
CatG is an essential protease for regulating MHC I molecules
Patients with certain polymorphisms in the CTSG gene had lower risk for chronic postsurgical pain compared with wild-types.
These in vivo data provide, for the first time, compelling evidence of the collateral involvement of cathepsin G, NE, and proteinase 3 (zeige PRTN3 Antikörper) in cigarette smoke-induced tissue damage and emphysema
expression levels of ELANE (zeige ELANE Antikörper) and CTSG were determined by quantitative real-time PCR
Elastase and cathepsin G are elevated in the plasma of HD patients, originating from primed PMNLs. In these patients, chronic elevation of these enzymes contributes to cleavage of VE-cadherin (zeige CDH5 Antikörper) and possible disruption of endothelial integrity.
Cathepsin G is an antimicrobial protein with bacteriocidal activity against S. aureus and N. gonorrhoeae.
these findings present evidence of an arterial-specific recruitment pattern centered on CatG-instructed adhesion strengthening. The inhibition of this process could provide a novel strategy for treatment of arterial inflammation with limited side effects.
Cathepsin G activity may impair efferocytosis, which could lead to an accumulation of lesion-associated apoptotic cells and the accelerated progression of early atherosclerotic lesions to more complex lesions in Apoe (zeige APOE Antikörper)(-/-) mice.
SerpinB1 (zeige SERPINB1 Antikörper) is critical for maintaining polymorphonuclear neutrophils survival by antagonizing intracellular cathepsin G activity.
Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions.
NADPH oxidase (zeige NOX1 Antikörper) in antimicrobial host defense against A. fumigatus and B. cepacia, whereas the proteases neutrophil elastase (zeige ELANE Antikörper), cathepsin G, and lysosomal cysteine protease cathepsin C/ dipeptidyl peptidase I (zeige CTSC Antikörper) are dispensable
Cathepsin G and neutrophil elastase (zeige ELANE Antikörper) contribute to lung-protective immunity against mycobacterial infections in mice.
Inhibition of TGF-beta (zeige TGFB1 Antikörper) significantly reduces microvessel density in mammary tumor-induced bone lesions, mediated by decreased expression of both vascular endothelial growth factor (VEGF (zeige VEGF Antikörper)) and monocyte chemotactic protein (MCP)-1 (zeige CPT1B Antikörper).
neutrophil elastase (zeige ELANE Antikörper) and cathepsin G are inhibited by PAI-1 (zeige SERPINE1 Antikörper) mutants
cathepsin G activity at the tumor-bone interface plays an important role in mammary tumor-induced osteolysis through RANKL (zeige TNFSF11 Antikörper)
both Cat-G and PAR(4 (zeige F2RL3 Antikörper)) play key roles in generating and/or amplifying relapses in ulcerative colitis
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
, vimentin-specific protease