IRDye 800CW BoneTag Optical Probe

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BioImaging (BI)
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Hersteller Produkt- Nr.
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Marke BrightSite™,BoneTag™
Spezifität Bone
Produktmerkmale Calcium-chelating compounds have been used effectively for the detection of bone mineralization, growth, and morphological changes, including tetracycline derivatives, xylenol orange, alizarin, calcein, and fluorescein. These characteristics have been used to produce a near infrared (NIR) optical bone marker for small animal imaging. Using MC3T3-E1 (osteoblasts) in in vitro cell-based assays, the IRDye BoneTag shows specific binding characteristics. In vivo testing of IRDye BoneTag optical probes are effective for skeletal labeling for imaging, which is unabated several weeks post-administration.
calcium-chelating compound
Optical Probe
Upon receipt, store at -20 °C prior to reconstitution. Reconstituted product should be used immediately.
Reinigung 0.2 μm nylon membrane
Applikationshinweise in vivo: 2 nmol per mouse (25 grams)
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute with 0.5 mL sterile 1X PBS
Konzentration 0.02 nM/μL
Buffer PBS
Handhabung Protect from light.
Lagerung -20 °C
Bilder des Herstellers
Immunofluorescence (IF) image for IRDye 800CW BoneTag Optical Probe (ABIN2169596) IRDye 800CW BoneTag Optical Probe
Produkt verwendet in: Kovar, Xu, Draney, Cupp, Simpson, Olive: "Near-infrared-labeled tetracycline derivative is an effective marker of bone deposition in mice." in: Analytical biochemistry, Vol. 416, Issue 2, pp. 167-73, 2011 (PubMed).