omega-conotoxin GVIA
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- Target
- omega-conotoxin GVIA
- Applikation
- Blocking Reagent (BR)
- Verwendungszweck
- omega-conotoxin GVIA blocks Cav2.2
- Sequenz
- H-Cys1-Lys-Ser-Hyp-Gly-Ser-Ser-Cys8-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys15-Cys16-Arg-Ser-Cys19-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys26-Tyr-NH2Hyp: hydroxypro line(Disulfide bonds between Cys1-Cys16, Cys8-Cys19 and Cys15-Cys26)
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Target
- omega-conotoxin GVIA
- Hintergrund
- Omega-conotoxin GVIA has been isolated from the venom of the cone Conus eographus. Omega-conotoxin GVIA acts at presynaptic membranes. It binds and blocks specifically Cav2.2 channel with an ED50 of 68pM.
- Molekulargewicht
- 3036.05 Da
- CAS-Nummer
- 106375-28-4
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