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The powerful Cell Cycle Chromobody® enables you to screen for compounds such as cancer drugs for effects on the cell cycle and toxicity in one experiment. You can apply this HCA assay in early drug development and validation as well as in basic research. Cell Cycle Chromobody® visualizes proliferating cell nuclear antigen (PCNA), the homotrimeric ringshaped protein that encircles the DNA and acts as a stationary loading platform for multiple, transiently interacting factors participating in various DNA transactions. As an essential cellular component, Features of Cell Cycle Chromobody:Trace dynamic changes during the cell cycle in real timeMonitor the distribution of an endogenous cell cycle marker protein - in comparison to fluorescent fusion proteins no overexpression artifact or cytotoxic effectsDoes not affect cellular functionsAlso available as stable fluorescent HeLa and U2OS cell lines ready to go for cellular screening.