serum/glucocorticoid Regulated Kinase Family, Member 3 Proteine (SGK3)

SGK3 is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. Zusätzlich bieten wir Ihnen serum/glucocorticoid Regulated Kinase Family, Member 3 Antikörper (128) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SGK3 23678 Q96BR1
SGK3 170755 Q9ERE3
SGK3 171498  
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Top serum/glucocorticoid Regulated Kinase Family, Member 3 Proteine auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
$311.24
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 11 Days
$291.50
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Insektenzellen Human GST tag 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$1,502.67
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,406.33
Details

SGK3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus) ,

Weitere Proteine zu serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) Interaktionspartnern

Human serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) Interaktionspartner

  1. Mechanism of activation of SGK3 by IGF1 via the class 1 and class 3 phosphatidylinositol 3-kinases has been described.

  2. Hence, we concluded that miR1443p, which is frequently downregulated in hepatocellular carcinoma (HCC) can inhibit proliferation, migration and repress angiogenesis by regulating SGK3 activation with PI3K independent signal pathway, and acts as a prognostic factor for HCC patients.

  3. SGK3 a kinase transcriptionally regulated by estrogen receptor alpha (ERalpha) in breast cancer, sustains ERalpha signaling and drives the acquired aromatase inhibitors resistance by protecting against endoplasmic reticulum (EnR) stress-induced ERalpha downregulation and cell death through preserving SERCA2b function.

  4. High SGK3 expression is associated with epithelial-mesenchymal transition in hepatocellular carcinoma.

  5. These findings highlight the importance of the hVps34-SGK3 pathway in counteracting inhibition of PI3K/Akt signalling.

  6. Data show that activation of serum- and glucocorticoid-regulated kinase 3 (SGK3) plays an important role in inositol polyphosphate 4-phosphatase type II (INPP4B)-mediated melanoma cell proliferation.

  7. It is unlikely that SGK3 plays a significant role for oncogenic signalling in multiple myeloma.

  8. SGK3 is a key mediator of PDK1 activity in melanoma.

  9. VPS34-IN1 will provide a useful tool to decipher the kinase-dependent functions of Vps34, with acute changes in SGK3 phosphorylation and subcellular localization being new biomarkers of Vps34 activity

  10. Breast cancers harboring oncogenic PIK3CA activate SGK3 signaling while suppressing Akt, indicative of oncogenic functions for both INPP4B and SGK3 in these tumors.

  11. SGK3 is an androgen receptor (AR) target and induces cell proliferation through the AR-SGK3-p70S6K-cyclin D1 pathway in prostate cancer cells.

  12. SGK3 is a novel regulator of K(ir)2.1.

  13. SGK3 stability and kinase activation are regulated by the Hsp90-Cdc37 chaperone complex.

  14. SGK1,3 enhances the expression level of mature hERG channels by inhibiting Nedd4-2 as well as by promoting Rab11-mediated hERG recycling.

  15. A positive correlation between SGK3 expression and breast tumor prognosis.

  16. found that expression of SGK3, which like AKT is activated by PI3K/PDK1 signaling, has more significance than overexpression of AKT in predicting poor outcome in hepatocellular carcinoma patients

  17. SGK3 is an estrogen receptor (ER) transcriptional target and promotes estrogen-mediated cell survival of ER-positive breast cancer cells.

  18. SGK3 is not required for insulin-induced PFK-2 activation and that this effect is likely mediated by PKBalpha.

  19. Glucocorticoid inducible kinase isoforms SGK1-3 are novel potent stimulators of Slc6a19 and may thus participate in the regulation of neutral amino acid transport in vivo.

  20. Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3beta) at serine-9 through direct interaction

Mouse (Murine) serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) Interaktionspartner

  1. Taken together, these data strongly suggest that SGK3 plays a significant role in regulating podocyte function, likely by controlling the expression and activity of GSK3.

  2. SGK1 and SGK3 are expressed in multiple microglial cell lines. SGK1 and SGK3 may play an important role in regulating microglial viability and inflammatory responses.

  3. SGK3 is a positive regulator of KCNA5, which is at least partially effective by abrogating the effect of Nedd4-2.

  4. SGK3 contributes to the regulation of store-operated calcium entry into and migration of dendritic cells.

  5. SGK3 plays a previously unappreciated role in glucose homeostasis, likely through direct effects within pancreatic beta-cells, to stimulate proliferation and insulin release

  6. The study identifies SGK3 as a novel endosomal kinase that acutely regulates Na(+)/H(+) exchanger 3 (NHE3) in a PI3K-dependent mechanism.

  7. SGK3 has a subtle but significant role in the regulation of renal tubular phosphate transport and bone density.

  8. Data suggest that SGK3 is critical for proper mast cell function.

  9. CISK-PX dimerizes in the presence of the linker between the PX domain and kinase domain, suggesting a multivalent mechanism in membrane localization of CISK

  10. role for SGK3 in normal postnatal hair follicle development, possibly involving effects on beta-catenin/Lef-1-mediated gene transcription

  11. SGK3 is differentially regulated in hippocampus after contextual fear conditioning & reactivation of the context-shock memory. Consolidation changes are recapitulated during reconsolidation. Retrieval-induced transcription depends on memory remoteness.

  12. SGK3, and to a lesser extent SGK2, but not SGK1, increase glutamate-induced currents by increasing the abundance of GluR1 protein in the cell membrane

  13. SGK3 is required for adequate intestinal Na(+) coupled glucose transport and impaired glucose absorption may contribute to delayed growth and decreased plasma glucose concentrations of SGK3 deficient mice.

  14. These results reveal a novel and important function for Sgk3 in controlling life and death in the hair follicle.

  15. Lack of SGK3 leads to subtle behavioral defects which may result from deranged neuronal regulation of transporters and ion channels.

  16. The sgk1(-/-)/sgk3(-/-) mice share the delayed hair growth with sgk3(-/-) mice and the modestly impaired renal salt retention with sgk1(-/-) mice.

  17. SGK3 is a very important and characteristic molecule that plays a critical role in both hair follicle morphogenesis and hair cycling.

  18. SGK3 mutation responsible for fuzzy hair phenotype in mice

  19. These findings support the model that CISK phosphorylates FLII and activates nuclear receptor transcription and suggest a new cell survival signaling pathway mediated by PI 3-kinase and CISK.

  20. SGK3 and Akt2 both appear to play important roles in postnatal hair follicle morphogenesis, likely because of their redundant regulation of beta-catenin-dependent transcriptional processes, which control hair follicle cell proliferation

serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3) Protein Überblick

Protein Überblick

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit SGK3

  • serum/glucocorticoid regulated kinase family member 3 (SGK3)
  • serum/glucocorticoid regulated kinase 3 (Sgk3)
  • serum/glucocorticoid regulated kinase family, member 3 (Sgk3)
  • serine/threonine-protein kinase Sgk3 (LOC464217)
  • serum/glucocorticoid regulated kinase family, member 3 (sgk3)
  • serine/threonine-protein kinase Sgk3 (LOC100231693)
  • serine/threonine-protein kinase Sgk3 (LOC100343709)
  • serum/glucocorticoid regulated kinase family, member 3 (SGK3)
  • serine/threonine-protein kinase Sgk3 (LOC100052030)
  • serine/threonine-protein kinase Sgk3 (LOC100521447)
  • 2510015P22Rik Protein
  • A330005P07Rik Protein
  • Cisk Protein
  • fy Protein
  • fz Protein
  • SGK2 Protein
  • Sgkl Protein
  • zgc:162253 Protein

Bezeichner auf Proteinebene für SGK3

cytokine-independent survival kinase , serine/threonine-protein kinase Sgk3 , serine/threonine protein kinase CISK , serum/glucocorticoid-regulated kinase 3 , serum/glucocorticoid regulated kinase 3 , serum glucocorticoid regulated kinase 3

GENE ID SPEZIES
23678 Homo sapiens
170755 Mus musculus
171498 Rattus norvegicus
420167 Gallus gallus
464217 Pan troglodytes
564523 Danio rerio
100231693 Taeniopygia guttata
100343709 Oryctolagus cuniculus
486981 Canis lupus familiaris
100052030 Equus caballus
100521447 Sus scrofa
504480 Bos taurus
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