serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 Proteine (SERPINA1)

The protein encoded by SERPINA1 is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Zusätzlich bieten wir Ihnen SERPINA1 Antikörper (437) und SERPINA1 Kits (52) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SERPINA1 12321 O35887
SERPINA1 5265 P01009
SERPINA1 24648 P17475
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Top SERPINA1 Proteine auf antikoerper-online.de

Showing 10 out of 46 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
HEK-293 Cells Human His tag 10 μg Anmelden zum Anzeigen 2 bis 3 Tage
$235.00
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$860.20
Details
HEK-293 Cells Human His tag Human Serpin A1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Anmelden zum Anzeigen 11 Days
$308.00
Details
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$600.88
Details
Human Cells Ratte His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$547.80
Details
Human Human Unkonjugiert 1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$95.00
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$251.74
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

SERPINA1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

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Rat (Rattus) , ,

Am meisten referenzierte SERPINA1 Proteine

  1. Human SERPINA1 Protein expressed in HEK-293 Cells - ABIN2714593 : Yao, Guihard, Blazquez-Medela, Guo, Moon, Jumabay, Boström, Yao: Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification. in Circulation research 2015 (PubMed)

Weitere Proteine zu serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Interaktionspartnern

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Interaktionspartner

  1. Extracellular calumenin regulates fibulin-1 to have crucial roles in ERK1/2 signaling and cell migration.

  2. This study points to a possible important role of calumenin (zeige CALU Proteine) in migration and differentiation of neurons

  3. Regions of 132-222 amino acids of calumenin (zeige CALU Proteine) and 853-892 amino acids of SERCA2 (zeige ATP2A2 Proteine) are the major binding partners.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Interaktionspartner

  1. Compound heterozygous Alpha-1 antitrypsin Pi*SZ genotype is relatively frequent in Caucasian subjects resident in Europe, and in their descendants residing in the American continent, Australia, and New Zealand.

  2. The mean cerebrospinal fluid signals of the most acidic serpinA1 isoform differed significantly between Parkinson patients with dementia, without dementia and healthy controls. Patients above the cut-off of 6.4 have a more than six times higher risk for an association with dementia compared to patients below the cut off.

  3. This study suggested that high a1-antitrypsin (AAT (zeige SERPINA1A Proteine))expression might be a negative prognostic marker for lung adenocarcinoma. AAT (zeige SERPINA1A Proteine) promoted lung adenocarcinoma metastasis, whose functional target may be fibronectin (zeige FN1 Proteine) . Our findings provide new insight into the mechanisms of lung adenocarcinoma metastasis

  4. this study identified a carbamylated peptide of A1AT as an antigenic target of autoantibodies in patients with rheumatoid arthritis

  5. Novel RNA-binding activity of NQO1 (zeige NQO1 Proteine) promotes SERPINA1 mRNA translation.

  6. ZAAT ER clearance resulted from enhancing ERdj3 (zeige DNAJB11 Proteine)-mediated ZAAT degradation by silencing ERdj3 (zeige DNAJB11 Proteine) while simultaneously enhancing autophagy. In this context, ERdj3 (zeige DNAJB11 Proteine) suppression may eliminate the toxic gain of function associated with polymerization of ZAAT

  7. In this study, the contribution of rare SERPINA1 alleles into AATD should not be neglected in the diagnosis practice given there is a wide spectrum of variants originated by mutation and sometimes shuffled between chromosomes by recombination.

  8. evaluation of serum proteins reveals that SERPINA1, SERPINA3 (zeige SERPINA3 Proteine) and SERPINC1 (zeige SERPINC1 Proteine) could be useful to discriminate healthy from colorectal carcinoma patients with a high sensitivity and specificity

  9. Alpha-1-antitrypsin for the treatment of steroid-refractory acute gastrointestinal graft-versus-host disease.

  10. this study proved that SYVN1 (zeige SYVN1 Proteine) enhances SERPINA1(E342K)/ATZ degradation through SQSTM1 (zeige SQSTM1 Proteine)-dependent autophagy and attenuates SERPINA1(E342K)/ATZ cytotoxicity.

Chimpanzee serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Interaktionspartner

  1. The mechanism underlying the alpha(1)PI deficiency that attends HIV-1 infection, was investigated.

Cow (Bovine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Interaktionspartner

  1. Comparisons of the expression patterns of cattle fetuses and their dams show that the PI gene is biallelically expressed in fetuses and predominantly monoallelically expressed in the dams.

SERPINA1 Protein Überblick

Protein Überblick

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit SERPINA1

  • alpha-1-antiproteinase F precursor (LOC100008973)
  • serpin family A member 1 (SERPINA1)
  • calumenin (Calu)
  • calumenin (CALU)
  • serpin family A member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog (serpina1.S)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SPIA1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog (serpina1.L)
  • 9530075H20Rik Protein
  • A1A Protein
  • A1AT Protein
  • AAT Protein
  • alpha-1-PI Protein
  • alpha1AT Protein
  • MGC64429 Protein
  • Pi Protein
  • PI1 Protein
  • PRO2275 Protein
  • SERPINA1 Protein
  • serpina1d Protein
  • Spi1 Protein

Bezeichner auf Proteinebene für SERPINA1

APF , alpha-1-antiproteinase F , alpha-1-antitrypsin , alpha-1-proteinase inhibitor , alpha-1 protease inhibitor , alpha-1-antiproteinase , serpin A1 , alpha-1 antitrypsin , protease inhibitor 1 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1 , crocalbin , crocalbin-like protein , alpha-1-antitrypsin null , protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin , serine (or cysteine) proteinase inhibitor, clade A, member 1 , alpha-1-antitrypsin (protease inhibitor) , alpha-1-protease inhibitor , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine protease inhibitor alpha 1 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine (or cysteine) proteinase inhibitor, clade A, member 1d , protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1) , serine proteinase inhibitor, clade A, member 1 , alpha 1 antitrypsin , Alpha-1 protease inhibitor , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog

GENE ID SPEZIES
100008973 Oryctolagus cuniculus
100171544 Pongo abelii
443388 Ovis aries
12321 Mus musculus
397301 Sus scrofa
100056849 Equus caballus
5265 Homo sapiens
24648 Rattus norvegicus
379963 Xenopus laevis
397688 Sus scrofa
423434 Gallus gallus
467541 Pan troglodytes
701361 Macaca mulatta
100145012 Xenopus (Silurana) tropicalis
423435 Gallus gallus
280699 Bos taurus
100729285 Cavia porcellus
480422 Canis lupus familiaris
101841330 Mesocricetus auratus
397792 Xenopus laevis
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