serine/threonine Kinase 24 Proteine (STK24)

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. Zusätzlich bieten wir Ihnen serine/threonine Kinase 24 Antikörper (98) und serine/threonine Kinase 24 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
STK24 8428 Q9Y6E0
STK24 223255 Q99KH8
STK24 361092 B0LT89
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Top serine/threonine Kinase 24 Proteine auf antikoerper-online.de

Showing 10 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Baculovirus infected Insect Cells Human His tag 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
$388.88
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,201.00
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$363.67
Details
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 3 bis 4 Tage
$310.00
Details

STK24 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine) ,

Rat (Rattus)

Weitere Proteine zu serine/threonine Kinase 24 (STK24) Interaktionspartnern

Human serine/threonine Kinase 24 (STK24) Interaktionspartner

  1. Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation.

  2. High MST3 expression is associated with breast cancer.

  3. This study demonistrated that MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development.

  4. This review notes that in the SOK1 and MST4 germinal center kinase III family of proteins, exon 1 encodes a 5' untranslated region, but this is not the case for MST3.

  5. These data provide molecular understanding of the mechanism by which MO25 isoforms regulates the activity of STE20 family protein kinases.

  6. results show that a STRADalpha-rac1-PAK1 pathway regulates cell polarity and invasion in LKB1-null cells. It also suggests that while the function of LKB1 and STRADalpha undoubtedly overlap, they may also have mutually exclusive roles

  7. mechanism of regulation of MST3

  8. Striatin orchestrates the regulation of Mst3 by PP2A.

  9. Mst3 is up-regulated and plays an important role in hypoxia-induced apoptosis of human trophoblasts.

  10. five crystal structures of the catalytic domain of MST3 are presented, including a complex with ADP and manganese, a unique cofactor preferred by the enzyme, and a complex with adenine.

  11. The mammalian sterile 20-like serine/threonine protein kinase 3 (Mst3) plays an essential role in the staurosporine-induced apoptosis of HeLa cells.

  12. Proteolytic activation of Mst3 by caspases.

  13. Mst3 contains signals which may cooperate to control the subcellular distribution of Mst3.

  14. Activation of NDR2 is a multistep process involving phosphorylation of the hydrophobic motif site Thr444/2 by MST3.

  15. MST3 inhibits cell migration in a fashion dependent on autophosphorylation and may regulate paxillin phosphorylation through tyrosine phosphatase PTP-PEST

  16. study demonstrated the essential role of Mst3, a human Ste20-like protein kinase, in the oxidative stress-induced apoptosis of trophoblasts of term placenta in normal spontaneous delivery

  17. Our results reveal that H2O2-induced MST3-mediated cell death involves suppressing both a JNK survival pathway and up-regulation of HO-1.

Mouse (Murine) serine/threonine Kinase 24 (STK24) Interaktionspartner

  1. our study reveals a role of Mst1-Mst2 in maintaining the Treg cell pool and functional fitness in vivo, by amplifying IL-2R-STAT5 signal strength and promoting Treg cell migratory ability and access to IL-2.

  2. show that the kinases Mst1 and Mst2 (Mst1/2) sense ROS and maintain cellular redox balance by modulating the stability of antioxidant transcription factor Nrf2.

  3. This is the first study reporting that MST3, a Ste20-like kinase, exerts a conserved regulatory role in sodium homeostasis after high-salt diet and in the development of hypertension.

  4. findings identify Mst1/2 as selective drivers of CD8alpha(+) dendritic cell function by integrating metabolic activity and cytokine signalling, and highlight that the interplay between immune signalling and metabolic reprogramming underlies the unique functions of dendritic cell subsets

  5. MST3 inhibits the insulin signalling pathway and is important in the development of insulin resistance and impaired blood glucose levels after an HFD.

  6. It is involved in apoptosis and serine/threonine kinase 3 (STK3) is a recently identified caspase-6 substrate.

  7. Using a standard two-thirds partial hepatectomy (PH) model in young and aged mice, the activity of the core kinases MST1 and LATS1 increased during the early hypertrophic phase and returned to steady state levels in the proliferative phase, coinciding with activation of YAP1 target genes and hepatocyte proliferation.

  8. Studies indicate that Hippo (Hpo; MST1/2 in mammals) signaling pathway plays a central role in the cell fate-specification process.

  9. Mst2 is involved in bone homeostasis, functioning as a reciprocal regulator of osteoclast and osteoblast differentiation through the NF-kappaB pathway

  10. the TLR-Mst1-Mst2-Rac signaling axis is critical for effective phagosome-mitochondrion function and bactericidal activity

  11. Hippo signaling is an endogenous repressor of adult cardiomyocyte renewal and regeneration.

  12. These data indicate that that inhibition of mammalian sterile 20-like kinase 1 rescued cardiac fibrosis and myocardial dysfunction in chronic beta1-adrenergic receptor stimulation-induced cardiomyopathy

  13. Phosphorylation of LC3 by the STK3 and STK4 is essential for autophagy.

  14. These results identify MST2, not MST1, as a critical regulator of caspase-mediated photoreceptor cell death in the detached retina and indicate its potential as a future neuroprotection target.

  15. results reveal a novel role of Mst2 in stress-dependent cardiac hypertrophy and remodeling in the adult mouse and likely human heart

  16. Mst1/2 regulate placental development by control of trophoblast cell differentiation and labyrinthine vasculature at midgestation and Mst1/2 control labyrinth morphogenesis in trophoblast- and fetal endothelial-dependent manners.

  17. Mst3 phosphorylates RhoA at Ser26, thereby negatively regulating the activity of RhoA in neurons.

  18. results showed that Mst1/Mst2 are required for proper cardiac lineage cell development and teratoma formation.

  19. these findings indicate that Mst1/2 are important for controlling Treg development and preventing autoimmunity in mice, but also shed new light on our understanding of Mst1 deficiency-mediated human immunodeficiency syndrome.

  20. STK24 appears to suppress exocytosis by interacting and competing with UNC13D C2B domain for lipid binding, whereas CCM3 has dual roles in exocytosis regulation.

Zebrafish serine/threonine Kinase 24 (STK24) Interaktionspartner

  1. CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.

Cow (Bovine) serine/threonine Kinase 24 (STK24) Interaktionspartner

  1. Mst3b, a neuron-specific homolog of the yeast kinase Ste20, is critical for axon outgrowth. Mst3b is activated in response to trophic factors, and suppressing its expression

serine/threonine Kinase 24 (STK24) Protein Überblick

Protein Überblick

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3\; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2\; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000

Genbezeichner und Symbole assoziert mit STK24

  • serine/threonine kinase 24 (STK24)
  • serine/threonine kinase 24 (Stk24)
  • serine/threonine kinase 24b (STE20 homolog, yeast) (stk24b)
  • serine/threonine-protein kinase 24 (ATEG_04314)
  • serine/threonine-protein kinase 24 (ATEG_09179)
  • serine/threonine-protein kinase 24 (UREG_03984)
  • serine/threonine-protein kinase 24 (BDBG_07988)
  • serine/threonine-protein kinase 24 (MCYG_07323)
  • serine/threonine kinase 3 (Stk3)
  • serine/threonine kinase 24 L homeolog (stk24.L)
  • 0610042I06Rik Protein
  • 1810013H02Rik Protein
  • C76483 Protein
  • mess1 Protein
  • MST Protein
  • MST-3 Protein
  • Mst2 Protein
  • mst3 Protein
  • mst3b Protein
  • RGD1561742 Protein
  • ste20 Protein
  • stk3 Protein
  • stk24 Protein
  • wu:fi29b08 Protein
  • zgc:66137 Protein

Bezeichner auf Proteinebene für STK24

STE20-like kinase 3 , STE20-like kinase MST3 , mammalian STE20-like protein kinase 3 , serine/threonine kinase 24 (STE20 homolog, yeast) , serine/threonine-protein kinase 24 , sterile 20-like kinase 3 , mammalian sterile twenty 3 kinase , MST-2 , STE20-like kinase MST2 , mammalian STE20-like protein kinase 2 , protein kinase homolog , serine/threonine-protein kinase 3 , serine/threonine kinase 24 (STE20 homolog) , serine/threonine kinase 24 L homeolog

GENE ID SPEZIES
8428 Homo sapiens
223255 Mus musculus
361092 Rattus norvegicus
406786 Danio rerio
418780 Gallus gallus
4320306 Aspergillus terreus NIH2624
4353910 Aspergillus terreus NIH2624
8444766 Uncinocarpus reesii 1704
8508737 Ajellomyces dermatitidis SLH14081
9227971 Arthroderma otae CBS 113480
100101492 Bos taurus
56274 Mus musculus
444155 Xenopus laevis
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