rho Guanine Nucleotide Exchange Factor (GEF) 15 Proteine (ARHGEF15)

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. Zusätzlich bieten wir Ihnen rho Guanine Nucleotide Exchange Factor (GEF) 15 Antikörper (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte ARHGEF15 ARHGEF15 287418  
ARHGEF15 22899 O94989
ARHGEF15 442801 Q5FWH6
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top rho Guanine Nucleotide Exchange Factor (GEF) 15 Proteine auf antikoerper-online.de

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
Details

ARHGEF15 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) Interaktionspartnern

Human rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) Interaktionspartner

  1. pathological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment

  2. upregulation of ARHGEF15 contributes to the development of aggressive PDAC by increasing the growth and motility of the pancreatic cancer cells, thereby worsening the prognosis of these patients.

  3. Arhgef15 acts as an endothelial cell-specific GEF to mediate VEGF-induced Cdc42 activation and potentiate RhoJ inactivation, thereby promoting actin polymerization and cell motility.

  4. This paper presents functional studies determined in rat, mouse, and human tissues and cell lines.

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) Interaktionspartner

  1. pathological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment

  2. The data of this study support a model in which Ephexin5 serves a dual role in spinogenesis, acting both as a brake on overall spine outgrowth and as a necessary component in the site-specific formation of new spines

  3. Study identified a RhoA guanine nucleotide exchange factor, Ephexin5, which negatively regulates excitatory synapse development until EphrinB binding to the EphB receptor triggers Ephexin5 phosphorylation, ubiquitination, and degradation.[Ephexin5]

rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15) Protein Überblick

Protein Überblick

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit ARHGEF15

  • Rho guanine nucleotide exchange factor 15 (Arhgef15)
  • Rho guanine nucleotide exchange factor 15 (ARHGEF15)
  • Rho guanine nucleotide exchange factor (GEF) 15 (Arhgef15)
  • ARGEF15 Protein
  • ARHGEF15 Protein
  • D130071N09 Protein
  • D530030K12Rik Protein
  • E5 Protein
  • Ephexin5 Protein
  • Vsm-RhoGEF Protein

Bezeichner auf Proteinebene für ARHGEF15

ephexin-5 , rho guanine nucleotide exchange factor 15 , Rho guanine nucleotide exchange factor (GEF) 15 , Rho guanine exchange factor 15 , rho guanine nucleotide exchange factor 15-like , Rho GEF 15 , Rho guanine exchange factor (GEF) 15

GENE ID SPEZIES
287418 Rattus norvegicus
454465 Pan troglodytes
489492 Canis lupus familiaris
512021 Bos taurus
721968 Macaca mulatta
100350440 Oryctolagus cuniculus
100404756 Callithrix jacchus
100589438 Nomascus leucogenys
100627972 Sus scrofa
22899 Homo sapiens
442801 Mus musculus
Ausgewählte Anbieter für rho Guanine Nucleotide Exchange Factor (GEF) 15 Proteine (ARHGEF15)
Haben Sie etwas anderes gesucht?