anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) Antikörper

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Zusätzlich bieten wir Ihnen GABRA2 Kits (23) und GABRA2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GABRA2 2555 P47869
GABRA2 289606  
GABRA2 14395 P26048
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Top anti-GABRA2 Antikörper auf antikoerper-online.de

Showing 10 out of 74 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GABRA2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: GABRA2 Sample Type: OVCAR-3 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of GABRA2 Antibody (C-term) (ABIN653245) in NCI-H460, MDA-MB435 cell line lysates (35 µg/lane). GABRA2 (arrow) was detected using the purified polyclonal antibody. GABRA2 Antibody (C-term) (ABIN653245) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Maus Kaninchen Unkonjugiert WB Western blot of 10 ?g of rat cortex lysate showing immunolabeling of the ~53k ?2-subunit of the GABAA-R. Western Blot: GABA A Receptor alpha 2 Antibody [ABIN152495] - Western blot of 10 ug of rat brain lysate showing immunolabeling of the ~53 kda GABAaR a2. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of mouse brain, using GABRA2 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Kaninchen Unkonjugiert IP, WB dilution: 1 : 1000, sample: unboiled synaptic membrane fraction of rat brain (LP1) 200 μL Anmelden zum Anzeigen 5 bis 6 Tage
$358.05
Details
Human Meerschweinchen Unkonjugiert ICC, IP, WB dilution: 1 : 1000, sample: unboiled synaptic membrane fraction of rat brain (LP1) Indirect immunostaining of hippocampus neurons (dilution 1 : 500). 100 μL Anmelden zum Anzeigen 5 bis 6 Tage
$358.05
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of GABRA2 staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of GABRA2 expression in mouse brain (A), rat brain (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti GABRA2/GABA A Receptor alpha 2 Polyclonal Antibody, Unconjugated (ABIN1387528) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse brain lysates probed with Rabbit Anti-GABRA2/GABA A Receptor alpha 2 Polyclonal Antibody, Unconjugated  ) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:5000 for 90 min at 37˚C. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details

GABRA2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GABRA2 Antikörper

  1. Human Polyclonal GABRA2 Primary Antibody für ICC, IP - ABIN1742454 : Herrera-Molina, Sarto-Jackson, Montenegro-Venegas, Heine, Smalla, Seidenbecher, Beesley, Gundelfinger, Montag: Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. in The Journal of biological chemistry 2014 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal GABRA2 Primary Antibody für WB - ABIN2792259 : Hadingham, Wingrove, Le Bourdelles, Palmer, Ragan, Whiting: Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric ac in Molecular pharmacology 1993 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal GABRA2 Primary Antibody für IP, WB - ABIN1742453 : Ardi, Albrecht, Richter-Levin, Saha, Richter-Levin: Behavioral profiling as a translational approach in an animal model of posttraumatic stress disorder. in Neurobiology of disease 2016 (PubMed)

  4. Mouse (Murine) Polyclonal GABRA2 Primary Antibody für WB - ABIN152495 : Werner, Swihart, Rau, Jia, Borghese, McCracken, Iyer, Fanselow, Oh, Sonner, Eger, Harrison, Harris, Homanics: Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane. in The Journal of pharmacology and experimental therapeutics 2010 (PubMed)

Weitere Antikörper gegen GABRA2 Interaktionspartner

Rhesus Monkey gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) Interaktionspartner

  1. the developmental shift in GABA(A) receptor alpha subunit (zeige POLG Antikörper) expression continues through adolescence in primate dorsolateral prefrontal cortex

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) Interaktionspartner

  1. An uncorrected exploratory analysis revealed associations between GABBR2 (zeige GABBR2 Antikörper), GABRA2 and DRD2 (zeige DRD2 Antikörper) variants with transcranial magnetic stimulation measures of corticospinal excitability and cortical inhibition in Huntington's disease, as well as with age at onset.

  2. Our study findings showed COMT (zeige COMT Antikörper) polymorphism conferring risk and GABRA1 (zeige GABRA1 Antikörper) and GABRA2 polymorphism as a protective genotype for Indian male with alcohol dependence (AD)

  3. parental externalizing was associated with more life events, and the association between life events and subsequent adolescent externalizing varied as a function of GABRA2 genotype (p

  4. A GABRA2 x Parental Monitoring effect on externalizing behavior trajectory was observed, such that A-carriers were largely unaffected by parental monitoring, whereas trajectory for those with the GG genotype was affected by parental monitoring.

  5. GABRA2 SNPs directly predicted adolescent alcohol problems.

  6. Alcohol dependence-associated variation in GABRA2 is associated with differential expression of the entire cluster of GABAA (zeige GABRg1 Antikörper) subunit genes on chromosome 4p12 in neural stem cells.

  7. Recent drinking history (p = 0.01), and recent drinking history x genotype interaction (p = 0.01) were significantly associated with acute adaptation of the subjective responses to alcohol for the GABRA2 SNP rs279858.

  8. The results of this study support a growing body of evidence linking GABAA (zeige GABRg1 Antikörper) receptors with the development of alcohol tolerance, dependence and withdrawal symptoms

  9. GABRA2 is significantly associated with rule breaking in mid- to late adolescence, but not substance abuse symptomatology across adolescence.

  10. GABRA2 genetic variants play a role in antipsychotic-associated weight gain.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2) Interaktionspartner

  1. Findings suggest that ovarian cycle-related progesterone and neurosteroids regulate alpha2-GABA-A receptor expression in the hippocampus via a non-progesterone receptor (zeige PGR Antikörper) pathway, which may be relevant to menstrual-cycle related brain conditions.

  2. Results show that the expression levels of Gabra2, as well as of GABA receptor-mediated inhibitory neurotransmission, are reduced in Shank2 (zeige SHANK2 Antikörper) e6-7, but not in e7 KO mice compared with their own wild type littermates. Shank2 (zeige SHANK2 Antikörper) e6-7 KO mice treated with allosteric modulator for the GABAA (zeige GABRg1 Antikörper) receptor reverses spatial memory deficits, indicating that reduced inhibitory neurotransmission may cause memory deficits in Shank2 (zeige SHANK2 Antikörper).

  3. Pharmological manipulation by clobazam, a common anticonvulsant with preferential affinity for the GABRA2 receptor, revealed dose-dependent protection against hyperthermia-induced seizures in Scn1a (zeige SCN1A Antikörper)+/- mice. These findings support Gabra2 as a genetic modifier of the Scn1a (zeige SCN1A Antikörper)+/- mouse model of Dravet syndrome.

  4. Results indicate that 174 proteins were associated with gamma-aminobutyric acid receptor subunit alpha 2 (pHalpha2).

  5. Wild-type and mutant mice have similar baseline nociceptive sensitivities and develop similar hyperalgesia specifically targeting alpha2-GABAA (zeige GABRg1 Antikörper) receptors which exert their antihyperalgesic effect through enhanced spinal nociceptive control.

  6. GABRA2 subunit expression in hippocampus modulates neurogenesis through nuclear factor of activated T cell (zeige NFATC3 Antikörper) (NFATc)4 (zeige NFATC4 Antikörper) activity.

  7. Disrupting the clustering of GABAA (zeige GABRg1 Antikörper) receptor alpha2 subunits in the frontal cortex leads to reduced gamma-power and cognitive deficits.

  8. Recovery of function following alcoholic intoxication is regulated by Gabra2 and Gabra3 (zeige GABRA3 Antikörper) receptor subunits.

  9. These findings suggest that alpha2-containing GABA(A) receptors expressed in the CA3 (zeige CA3 Antikörper) region provide the inhibition that controls hippocampal rhythm during cholinergically induced oscillations

  10. The results of this study emphasize the critical role of GABAergic synaptic signaling for structural maturation of adult-born GCs (zeige UGCG Antikörper) and formation of glutamatergic synapses.

GABRA2 Antigen-Profil

Protein Überblick

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit GABRA2

  • gamma-aminobutyric acid type A receptor alpha2 subunit (GABRA2) Antikörper
  • gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1) Antikörper
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2 (gabra2) Antikörper
  • gamma-aminobutyric acid type A receptor alpha2 subunit (Gabra2) Antikörper
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2 S homeolog (gabra2.S) Antikörper
  • gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2) Antikörper
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 (Gabra2) Antikörper
  • C630048P16Rik Antikörper
  • Gabra-2 Antikörper

Bezeichner auf Proteinebene für GABRA2

GABA(A) receptor subunit alpha-2 , gamma-aminobutyric acid receptor subunit alpha-2 , GABA-A receptor alpha-1 subunit , gamma-aminobutyric acid (GABA) A receptor, alpha 2 , gamma-aminobutyric acid A receptor alpha 2 , gamma-aminobutyric acid A receptor, alpha 2 precursor-like , GABA(A) receptor, alpha 2 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 , gamma-aminobutyric acid receptor A2 subunit , gamma-aminobutyric acid A receptor, alpha 2

GENE ID SPEZIES
703894 Macaca mulatta
751992 Taeniopygia guttata
770511 Gallus gallus
100173835 Pongo abelii
100061914 Equus caballus
100170583 Xenopus (Silurana) tropicalis
100286789 Felis catus
100339376 Oryctolagus cuniculus
100546188 Meleagris gallopavo
2555 Homo sapiens
289606 Rattus norvegicus
447255 Xenopus laevis
482131 Canis lupus familiaris
282236 Bos taurus
461355 Pan troglodytes
14395 Mus musculus
Ausgewählte Anbieter für anti-GABRA2 (GABRA2) Antikörper
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