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GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Zusätzlich bieten wir Ihnen GABRA2 Kits (23) und GABRA2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 74 products:
Cow (Bovine) Polyclonal GABRA2 Primary Antibody für WB - ABIN2792259
Hadingham, Wingrove, Le Bourdelles, Palmer, Ragan, Whiting: Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric ac in Molecular pharmacology 1993
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Human Polyclonal GABRA2 Primary Antibody für ICC, IP - ABIN1742454
Herrera-Molina, Sarto-Jackson, Montenegro-Venegas, Heine, Smalla, Seidenbecher, Beesley, Gundelfinger, Montag: Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. in The Journal of biological chemistry 2014
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Mouse (Murine) Polyclonal GABRA2 Primary Antibody für WB - ABIN152495
Werner, Swihart, Rau, Jia, Borghese, McCracken, Iyer, Fanselow, Oh, Sonner, Eger, Harrison, Harris, Homanics: Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane. in The Journal of pharmacology and experimental therapeutics 2010
Human Polyclonal GABRA2 Primary Antibody für IP, WB - ABIN1742453
Ardi, Albrecht, Richter-Levin, Saha, Richter-Levin: Behavioral profiling as a translational approach in an animal model of posttraumatic stress disorder. in Neurobiology of disease 2016
the developmental shift in GABA(A) receptor alpha subunit (zeige POLG Antikörper) expression continues through adolescence in primate dorsolateral prefrontal cortex
GABA alpha2 and/or alpha3 receptor subtypes are involved in GABAergic modulation of prolactin (zeige PRL Antikörper) secretion.
An uncorrected exploratory analysis revealed associations between GABBR2 (zeige GABBR2 Antikörper), GABRA2 and DRD2 (zeige DRD2 Antikörper) variants with transcranial magnetic stimulation measures of corticospinal excitability and cortical inhibition in Huntington's disease, as well as with age at onset.
Our study findings showed COMT (zeige COMT Antikörper) polymorphism conferring risk and GABRA1 (zeige GABRA1 Antikörper) and GABRA2 polymorphism as a protective genotype for Indian male with alcohol dependence (AD)
parental externalizing was associated with more life events, and the association between life events and subsequent adolescent externalizing varied as a function of GABRA2 genotype (p = .05). The association between life events and subsequent adolescent externalizing was stronger for adolescents with 0 copies of the G minor allele compared to those with 1 or 2 copies of the minor allele
A GABRA2 x Parental Monitoring effect on externalizing behavior trajectory was observed, such that A-carriers were largely unaffected by parental monitoring, whereas trajectory for those with the GG genotype was affected by parental monitoring.
GABRA2 SNPs directly predicted adolescent alcohol problems.
Alcohol dependence-associated variation in GABRA2 is associated with differential expression of the entire cluster of GABAA (zeige GABRg1 Antikörper) subunit genes on chromosome 4p12 in neural stem cells.
Recent drinking history (p = 0.01), and recent drinking history x genotype interaction (p = 0.01) were significantly associated with acute adaptation of the subjective responses to alcohol for the GABRA2 SNP rs279858.
The results of this study support a growing body of evidence linking GABAA (zeige GABRg1 Antikörper) receptors with the development of alcohol tolerance, dependence and withdrawal symptoms
GABRA2 is significantly associated with rule breaking in mid- to late adolescence, but not substance abuse symptomatology across adolescence.
Findings suggest that ovarian cycle-related progesterone and neurosteroids regulate alpha2-GABA-A receptor expression in the hippocampus via a non-progesterone receptor (zeige PGR Antikörper) pathway, which may be relevant to menstrual-cycle related brain conditions.
Results show that the expression levels of Gabra2, as well as of GABA receptor-mediated inhibitory neurotransmission, are reduced in Shank2 (zeige SHANK2 Antikörper) e6-7, but not in e7 KO mice compared with their own wild type littermates. Shank2 (zeige SHANK2 Antikörper) e6-7 KO mice treated with allosteric modulator for the GABAA (zeige GABRg1 Antikörper) receptor reverses spatial memory deficits, indicating that reduced inhibitory neurotransmission may cause memory deficits in Shank2 (zeige SHANK2 Antikörper).
Pharmological manipulation by clobazam, a common anticonvulsant with preferential affinity for the GABRA2 receptor, revealed dose-dependent protection against hyperthermia-induced seizures in Scn1a (zeige SCN1A Antikörper)+/- mice. These findings support Gabra2 as a genetic modifier of the Scn1a (zeige SCN1A Antikörper)+/- mouse model of Dravet syndrome.
Results indicate that 174 proteins were associated with gamma-aminobutyric acid receptor subunit alpha 2 (pHalpha2).
Wild-type and mutant mice have similar baseline nociceptive sensitivities and develop similar hyperalgesia specifically targeting alpha2-GABAA (zeige GABRg1 Antikörper) receptors which exert their antihyperalgesic effect through enhanced spinal nociceptive control.
GABRA2 subunit expression in hippocampus modulates neurogenesis through nuclear factor of activated T cell (zeige NFATC3 Antikörper) (NFATc)4 (zeige NFATC4 Antikörper) activity.
Disrupting the clustering of GABAA (zeige GABRg1 Antikörper) receptor alpha2 subunits in the frontal cortex leads to reduced gamma-power and cognitive deficits.
Recovery of function following alcoholic intoxication is regulated by Gabra2 and Gabra3 (zeige GABRA3 Antikörper) receptor subunits.
These findings suggest that alpha2-containing GABA(A) receptors expressed in the CA3 (zeige CA3 Antikörper) region provide the inhibition that controls hippocampal rhythm during cholinergically induced oscillations
The results of this study emphasize the critical role of GABAergic synaptic signaling for structural maturation of adult-born GCs (zeige UGCG Antikörper) and formation of glutamatergic synapses.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
GABA(A) receptor subunit alpha-2
, gamma-aminobutyric acid receptor subunit alpha-2
, GABA-A receptor alpha-1 subunit
, gamma-aminobutyric acid (GABA) A receptor, alpha 2
, gamma-aminobutyric acid A receptor alpha 2
, gamma-aminobutyric acid A receptor, alpha 2 precursor-like
, GABA(A) receptor, alpha 2
, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2
, gamma-aminobutyric acid receptor A2 subunit
, gamma-aminobutyric acid A receptor, alpha 2