Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
GABRA1 encodes a gamma-aminobutyric acid (GABA) receptor. Zusätzlich bieten wir Ihnen gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 Proteine (5) und und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 331 products:
Mammalian Monoclonal GABRA1 Primary Antibody für ISt, IHC - ABIN1304642
Zhou, Ding, Deel, Ferrick, Emeson, Gallagher: Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome. in Neurobiology of disease 2014
Show all 27 Pubmed References
Human Polyclonal GABRA1 Primary Antibody für WB - ABIN152533
Herden, Pardo, Hajela, Yuan, Atchison: Differential effects of methylmercury on gamma-aminobutyric acid type A receptor currents in rat cerebellar granule and cerebral cortical neurons in culture. in The Journal of pharmacology and experimental therapeutics 2008
Show all 11 Pubmed References
Rat (Rattus) Monoclonal GABRA1 Primary Antibody für ICC, IHC - ABIN1742455
Acuna, Liu, Südhof: How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs. in Neuron 2016
Mouse (Murine) Polyclonal GABRA1 Primary Antibody für WB - ABIN152548
Roberts, Hu, Lund, Brooks-Kayal, Russek: Brain-derived neurotrophic factor (BDNF)-induced synthesis of early growth response factor 3 (Egr3) controls the levels of type A GABA receptor alpha 4 subunits in hippocampal neurons. in The Journal of biological chemistry 2006
Show all 2 Pubmed References
Gabra1 mutations significantly reduced surface expression of GABAARs in neurons and the alpha1A295D and alpha1T10'I mutations reduces expression in HEK293 cells. In addition, the alpha1D192N and alpha1T10'I mutations significantly accelerated the decay rate of GABAergic IPSCs. The alpha1T10'I mutation also reduced the number of GABAergic synaptic contacts in neurons.
This study showed that GABRA1 expression in lateral nucleus of amygdala and dentate gyrus, ca1 (zeige CA1 Antikörper) region and subiculum of hippocampus.
This study shown that the two SNPs located in the GABRA1 gene, rs4263535 (Pallele=0.002; uncorrected) and rs1157122 (Pallele=0.006; uncorrected) showed associated with Japanese individuals affected with schizophrenia.
Rs2279020 (GABRA1, G > A) variation was associated with a decreased risk of developing VPA-resistant epilepsy.
The results further substantiate the role of GABRA1 in phenytoin mode of action in epilepsy.
Our study findings showed COMT (zeige COMT Antikörper) polymorphism conferring risk and GABRA1 and GABRA2 (zeige GABRA2 Antikörper) polymorphism as a protective genotype for Indian male with alcohol dependence (AD)
The polymorphism of rs1129647 and rs2290733 of GABRA1 has a nominal relationship with amphetamine-induced psychotic disorder .
Study confirms GABRA1 mutations as significant contributors to the genetic etiology of both mild and severe epilepsy syndromes. GABRA1 mutations, through a possible mechanism of haploinsufficiency, cause an impairment of the GABA inhibitory function leading to a wide spectrum of epilepsy phenotypes.
This unique case not only allows to further define the phenotypic spectrum of infantile epileptic encephalopathy associated with rare de novo GABRA1 variants but exemplifies the need for a sensitive review of unclear associations in clinically defined syndromes and for extended diagnostic work-up in individuals with unusual presentations of a genetically confirmed diagnosis.
This study clarifies a Grp94 (zeige HSP90B1 Antikörper)-mediated ERAD pathway for GABAA (zeige GABRg1 Antikörper) receptors, which provides a novel way to finely tune their function in physiological and pathophysiological conditions.
GAPDH (zeige GAPDH Antikörper) directly phosphorylates the long intracellular loop of GABA(A) receptor alpha1 subunit at identified serine and threonine residues. GAPDH (zeige GAPDH Antikörper) and the alpha1 subunit were found to be colocalized at the neuronal plasma membrane.
Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA (zeige GABRg1 Antikörper)) receptors
This experiments show that loop F of the alpha-subunit (zeige POLG Antikörper) governs the potency of GABA on alpha2 and alpha5-GABAA (zeige GABRg1 Antikörper) receptors in vitro as well as in vivo.
This results of this study concluded that targeted deletion of Gabra1 causes moderate adaptations of GABAergic synapses in CA1 (zeige CA1 Antikörper) pyramidal cells
We used a low-affinity antagonist to show that GABAA (zeige GABRg1 Antikörper)-receptor saturation occurs at this synapse but does not underlie frequency-invariant transmission.
This study suggests that movement of loop G in the beta1 strand of the GABAA (zeige GABRg1 Antikörper) receptor alpha1 subunit is involved in a conformational rearrangement associated with channel activation
These data suggest that GABA, acting through both presynaptic GABAA (zeige GABRg1 Antikörper) and GABAB receptors, modulate the amplitude and short-term plasticity of excitatory synapses, a result not possible from activation of either receptor type alone
Nbea (zeige NBEA Antikörper) targets glutamate (zeige GRIN1 Antikörper) and GABA receptors to the synapse via distinct molecular pathways by interacting with specific effector proteins.
the identity and location of distinct GABAAR (zeige GABRG2 Antikörper) subunits within the cellular networks of the mouse dorsal raphe nucleus and that stress impacts on the expression levels of particular subunits at the gene and protein level
This study demonstrated that Adolescent-onset GABAA (zeige GABRg1 Antikörper) alpha1 silencing regulates reward-related decision making in mice.
Enduring loss of tonic but not phasic GABAAR (zeige GABRG2 Antikörper) currents critically contributes to the prolonged amygdala disinhibition subsequent to chronic stress.
these findings suggest that gephyrin (zeige GPHN Antikörper) may be a key factor in BDNF (zeige BDNF Antikörper)-dependent GABAAR (zeige GABRG2 Antikörper) regulation in the amygdala.
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
GABA(A) receptor subunit alpha-1
, GABA(A) receptor, alpha 1
, gamma-aminobutyric acid receptor subunit alpha-1
, gamma-aminobutyric acid A receptor, alpha 1
, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
, gamma-aminobutyric acid A receptor, alpha 1
, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
, GABAA alpha 1