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The enzyme encoded by GGT1 catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. Zusätzlich bieten wir Ihnen gamma Glutamyltransferase 1 Kits (60) und gamma Glutamyltransferase 1 Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 140 products:
Human Monoclonal GGT1 Primary Antibody für IHC (p), IP - ABIN561038
West, Segu, Feasley, Kang, Klouckova, Li, Novotny, West, Mechref, Hanigan: Analysis of site-specific glycosylation of renal and hepatic ?-glutamyl transpeptidase from normal human tissue. in The Journal of biological chemistry 2010
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Human Polyclonal GGT1 Primary Antibody für WB - ABIN1881373
Ikeda, Maki, Yin, Kawate, Adachi, Ohnaka, Takayanagi, Kono: Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index. in Scandinavian journal of clinical and laboratory investigation 2010
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Mouse (Murine) Polyclonal GGT1 Primary Antibody für WB - ABIN1881372
Aly, Lightfoot, El-Shemy: Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro. in Chemico-biological interactions 2009
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Human Polyclonal GGT1 Primary Antibody für IF, WB - ABIN516020
Scalise, Balia, Cianchetti, Neri, Carnicelli, Zucchi, Franzini, Corti, Paolicchi, Celi, Pedrinelli: Non enzymatic upregulation of tissue factor expression by gamma-glutamyl transferase in human peripheral blood mononuclear cells. in Thrombosis journal 2016
both tumor GGT and serum GGT are poor prognostic factors in gastric cancer
The GPR (zeige ALDH18A1 Antikörper) could be used as a non-invasive marker to predict liver fibrosis and cirrhosis in CHB-NAFLD (zeige TSC2 Antikörper) individuals.
This study demonstrated a positive association between serum GGT levels and LV diastolic dysfunction and LV hypertrophy in a large cohort of middle-aged men and women independent of potential confounders.
we found that serum exosomal GGT activity was significantly higher in prostate cancer (PC), patients than in benign prostatic hyperplasia (BPH) patients. In support of this finding, immunohistochemical analysis showed increased GGT1 expression in PC tissues compared with BPH tissues. Our results suggest that serum exosomal GGT activity could be a useful biomarker for PC
GGT activity may serve as a potential surrogate biomarker of atherogenic risk and metabolic health status
High initial GGT concentration and increases in GGT concentration over time should be considered independent predictors of and to have a combined effect on incident metabolic syndrome.
gamma-glutamyltransferase may have a role in nasopharyngeal carcinoma
Formation of LTD4 was rapid when catalyzed by gamma-glutamyl transpeptidase (GGT)1 in the A549 epithelial lung cancer cell line, but considerably slower when catalyzed by GGT5 (zeige GGT5 Antikörper) in primary bronchial epithelial cells. When A549 cells were cultured in the presence of IL-1beta (zeige IL1B Antikörper), GGT1 expression increased about 2-fold. Also exosomes from A549 cells contained GGT1 and augmented LTD4 formation.
Results show a weak genetic evidence that GGT levels may have a causal role in the development of type 2 diabetes.
The structure of DON-bound hGGT1 has led to the discovery of a new mechanism of inactivation by DON that differs from its inactivation of other glutamine (zeige GFPT1 Antikörper) metabolizing enzymes, and insight into the activation of the catalytic nucleophile that initiates the hGGT1 reaction.
the present study developed a liver-specific GGT-overexpressing mice model and found that GGT elevation in short term had no effects on glucose metabolism but could increase insulin (zeige INS Antikörper) sensitivity through enhancing the activity of insulin (zeige INS Antikörper) signaling pathway.
Statins can significantly decrease the expression of GGT in aortic atherosclerotic plaques of ApoE (zeige APOE Antikörper)-knockout mice.
Gamma-glutamyltransferase levels are an independent predictor of worsening kidney function and mortality in acute heart failure patients.
Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.
Mutations in the Ggt1 gene are responsible for the phenotypes of dwg/dwg and dwg(Bayer)/dwg(Bayer) mice.
prooxidant reactions mediated by gamma-GT in turn regulate the levels of tyrosinase (zeige TYR Antikörper) in pigment cells.
GGT regulates osteoclast biology at least partly independently of sex steroids
GGT stimulates RANKL (zeige TNFSF11 Antikörper) expression
GGT is implicated as being involved in diseases characterized by accelerated osteoclast development and bone destruction.
The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
, gamma-glutamyltranspeptidase 1
, GGT 1
, gamma-glutamyl transpeptidase
, glutathione hydrolase 1
, leukotriene-C4 hydrolase
, glutamyl transpeptidase
, gamma glutamyl-transferase 1
, gamma-glutamyltransferase 2
, ggt 1
, gamma-glutamyltransferase 1 a
, Gamma-glutamyltranspeptidase 1
, gamma-glutamyltranspeptidase 1-like
, Gamma-glutamyltransferase 1