beta-1,4-N-Acetyl-Galactosaminyl Transferase 1 (B4GALNT1) ELISA Kits

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. Zusätzlich bieten wir Ihnen B4GALNT1 Antikörper (51) und B4GALNT1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human B4GALNT1 B4GALNT1 2583 Q00973
Anti-Maus B4GALNT1 B4GALNT1 14421 Q09200
Anti-Ratte B4GALNT1 B4GALNT1 64828 Q10468
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Weitere ELISA Kits für B4GALNT1 Interaktionspartner

Human beta-1,4-N-Acetyl-Galactosaminyl Transferase 1 (B4GALNT1) Interaktionspartner

  1. Data suggest that ganglioside glycosyltransferases ST3GAL5 (zeige ST3GAL5 ELISA Kits), ST8SIA1 (zeige ST8SIA1 ELISA Kits), and B4GALNT1 are S-acylated at conserved cysteine residues located close to cytoplasmic border of their transmembrane domains; ST3Gal-II (zeige ST3GAL2 ELISA Kits) is acylated at conserved cysteine residue in N-terminal cytoplasmic tail; for B4GALNT1 and ST3Gal-II (zeige ST3GAL2 ELISA Kits), dimer formation controls their S-acylation status.

  2. Novel B4GALNT1 mutations reported in two families with hereditary spastic paraplegia.

  3. The resukts of this study identified mutations in B4GALNT1 (GM2 (zeige CYB5D2 ELISA Kits) synthase), encoding the enzyme that catalyzes the second step in complex ganglioside biosynthesis, as the cause of this neurodegenerative phenotype.

  4. Minimally disseminated disease in high risk retinoblastoma patients was detected using reverse transcriptase PCR for GD2 synthase mRNA in CSF (zeige CSF2 ELISA Kits).

  5. Molecular upstaging of GalNAc-T using rt-pcr was correlated with prognosis in melanoma patients

  6. GD2/GM2 (zeige CYB5D2 ELISA Kits) is not a reliable biomarker in small cell lung carcinoma

  7. The expression of three messengers coding for SAT-1 (zeige SAT1 ELISA Kits), SAT-2 (zeige SLC38A2 ELISA Kits) and GalNAcT-1 in human samples of intestinal cancer and some cell lines (breast cancer and melanomas), was evaluated.

  8. Transmission disequilibrium test and case-control analysis did not detect an association of B4GALNT1 gene with T1DM.

Mouse (Murine) beta-1,4-N-Acetyl-Galactosaminyl Transferase 1 (B4GALNT1) Interaktionspartner

  1. We used GM2/GD2 synthase (B4galnt1)-deficient mice to immunize by liposomes embedded with GD1alpha or acidic glycolipid fractions from brain of St3gal5 (zeige ST3GAL5 ELISA Kits)-deficient mice. Specificities of established mAbs as analyzed by enzyme-linked immunosorbent assay and thin-layer chromatography-immunostaining were very high among various gangliosides.

  2. GM2 (zeige CYB5D2 ELISA Kits) elevation is associated with activation of microglia and astrocytes in the injured developing brain, and GM2 (zeige CYB5D2 ELISA Kits), GD2, or other downstream gangliosides may regulate astroglial responses in ethanol-induced neurodegeneration

  3. This study demonistrated that Ganglioside deficiency(B4galnt1 and ST8SIA1 (zeige ST8SIA1 ELISA Kits) knockout mice causes inflammation and neurodegeneration via the activation of complement system in the spinal cord.

  4. Galgt1 is required for presynaptic expression of the CT carbohydrate at the neuromuscular junction.

  5. Impaired hippocampal long-term potentiation and failure of learning in beta1,4-N-acetylgalactosaminyltransferase gene transgenic mice

  6. To define maturation of cortical neurons in mice lacking B4galnt1 we performed a morphological analysis of Golgi-Cox (zeige CPOX ELISA Kits) impregnated pyramidal neurons.

  7. Our data indicate that it is highly unlikely that transmission failure at NMJs contributes to the progressive motor defects of aged GM2/GD2-synthase null-mutants.

  8. In GalNAc-T(-/-) mice, the number of degenerated axons was increased in the dorsal funiculus, tract of Lissauer, and dorsolateral funiculus of the cervical spinal cord as well as the dorsal funiculus and tract of Lissauer of the lumbar segment

  9. Increased 9-O-acetyl GD3, in addition to GM3 (zeige GRM6 ELISA Kits) and GD3, may play an important role in the compensation for deleted complex gangliosides in the mutant mice.

B4GALNT1 Antigen-Profil

Beschreibung des Gens

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit B4GALNT1

  • beta-1,4-N-acetyl-galactosaminyl transferase 1 L homeolog (b4galnt1.L) Antikörper
  • beta-1,4-N-acetyl-galactosaminyl transferase 1a (b4galnt1a) Antikörper
  • beta-1,4-N-acetyl-galactosaminyl transferase 1 (b4galnt1) Antikörper
  • Beta-1,4 N-acetylgalactosaminyltransferase 1 (b4gn1) Antikörper
  • beta-1,4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) Antikörper
  • beta-1,4-N-acetyl-galactosaminyl transferase 1 (B4galnt1) Antikörper
  • 4933429D13Rik Antikörper
  • B4GALNT1 Antikörper
  • Gal-NAc-T Antikörper
  • GALGT Antikörper
  • Galgt1 Antikörper
  • GalNAc-T Antikörper
  • GalNAcT Antikörper
  • Ggm-2 Antikörper
  • Ggm2 Antikörper
  • MGC53523 Antikörper
  • SPG26 Antikörper
  • zgc:158609 Antikörper

Bezeichner auf Proteinebene für B4GALNT1

beta-1,4-N-acetyl-galactosaminyl transferase 1 , beta-1,4 N-acetylgalactosaminyltransferase 1 , Beta-1,4 N-acetylgalactosaminyltransferase 1 , beta-1,4 N-acetylgalactosaminyltransferase 1-like , (N-acetylneuraminyl)-galactosylglucosylceramide , GD2 synthase, GM2 synthase , GM2/GD2 synthase , UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1 , UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T) , beta1,4GalNAc-T , beta1-4GalNAc-T , UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase , UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase , beta1,4GalNAC-T , beta-4N-acetylgalactosaminyltransferase

379299 Xenopus laevis
558684 Danio rerio
100145208 Xenopus (Silurana) tropicalis
100306792 Salmo salar
100441953 Pongo abelii
100516440 Sus scrofa
2583 Homo sapiens
481129 Canis lupus familiaris
520159 Bos taurus
14421 Mus musculus
64828 Rattus norvegicus
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